Journal of Nutrition

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Journal of Nutrition Vol. 23 No. 6 June 1942, pp. 545-553
Copyright © 1942 by American Society for Nutrition
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Relationship Between Pantothenic Acid Requirement and Age in the Rat

Two Figures

Klaus Unna and Grace V. Richards

Merck Institute for Therapeutic Research, Rahway, New Jersey

The pantothenic acid requirement at various stages of life was studied in albino and piebald rats maintained on a basal diet devoid of pantothenic acid.

1. The maintenance dose for optimal growth and for prevention of characteristic deficiency lesions decreases from 100 µg. per day at 3 weeks of age to 25 µg. per day at 10 weeks of age.
2. The requirement for pantothenic acid cannot be correlated with the weight or the food consumption of the rat.


Manuscript received 14 February 1942.





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