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Effect on Growth and Calcium Assimilation of Citric Acid—Potassium Citrate Mixtures¹

Department of Chemistry, Columbia University, New York City

Administration of a mixture of citric acid and potassium citrates, in approximately the proportions and quantities which would be supplied by 10 cc. of fresh orange juice daily, increased the rate of growth and the total calcium retention of young rats on a wheat-and-milk diet, but, unlike the orange juice tested earlier in a similar way, had no appreciable effect on the percentage of the dietary calcium which was retained in the body of the growing animal. It thus appears that orange juice favors calcium assimilation in growth through some property in addition to its content of citric acid and citrates and its preponderance of base-forming elements.

Manuscript received 11 September 1941.