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Journal of Nutrition Vol. 21 No. 1 January 1941, pp. 93-100
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A Study of the Need for Cobalt in Dogs on Milk Diets1

Three Figures

Douglas V. Frost, C. A. Elvehjem and E. B. Hart

Department of Biochemistry, College of Agriculture, University of Wisconsin Madison

In many cases iron and copper suffice with milk for normal hemoglobin building in dogs. The addition of small amounts of cobalt to iron and copper therapy stimulated hematopoiesis in certain dogs in which the rate of blood formation appeared unusually slow. About one-half of the dogs studied showed a cobalt deficiency as evidenced by hematopoietic responses to cobalt at a minimum level of 0.1 mg. per day.


1 Published with the approval of the Director of the Wisconsin Agricultural Experiment Station. This work was supported in part by a grant from the Works Progress Administration.

Manuscript received 3 September 1940.


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F. H. BETHELL, C. C. STURGIS, R. A. HETTIG, and O. T. MALLERY
BLOOD: A REVIEW OF THE RECENT LITERATURE
Arch Intern Med, May 1, 1942; 69(5): 856 - 926.
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