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Journal of Nutrition Vol. 21 No. 1 January 1941, pp. 13-24
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The Effect of the Quantity of Basal Food Intake upon the Utilization of Vitamin A1

Kathleen Dietrich Muelder2 and Eunice Kelly

Department of Foods and Nutrition, Division of Home Economics, Michigan State College, East Lansing

The influence of the quantity of basal food intake on vitamin A utilization has been studied by means of carefully controlled triads of rats as measured by rate of growth and incidence of "abscessed" areas. For the levels of vitamin A used in this experiment, the caloric intake was responsible for a greater proportion of the gain in weight during a 4-week period than was the unitage of vitamin A administered, the percentage of the gain in weight from caloric intake increasing at each elevation of vitamin intake. When the intake of vitamin A was identical in different groups of animals, the gain in weight was directly related to the quantity of basal diet consumed during the period of observation.

There was a highly significant reduction in number of "abscessed" areas by the administration of either 1, 3 or 6 International Units of vitamin A below the number of such areas exhibited by the negative groups, but no statistically significant difference between the levels of vitamin used in this experiment. The quantity of basal food intake showed no statistically significant influence upon incidence of "abscessed" areas. However, there was some indication of an advantage of unrestricted as compared with restricted food intake at the highest level (6 units) of vitamin A intake.

1 Approved by the director of the Michigan Agricultural Experimental Station for publication as Journal Article no. 457, n.s.

2 Formerly Assistant Professor of Foods and Nutrition and Research Assistant in Foods and Nutrition at Michigan State College, East Lansing, Michigan.

Manuscript received 28 August 1940.




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