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Studies on a Dermatitis in Chicks Distinct from Pantothenic Acid Deficiency¹

One Figure

Department of Biochemistry, College of Agriculture, University of Wisconsin, Madison

A typical dermatitis occurring in chicks fed purified rations adequate in pantothenic acid has been described. The properties of the protective factor agree with those reported for vitamin H and biotin and potent preparations of vitamin H have produced cures in 3 weeks when injected at a level of 35 µg. per day, the lowest level used.

Supported in part by grants from the Wisconsin Alumni Research Foundation and the Works Progress Administration project no. 8649.

We are indebted to Merck and Company, Rahway, New Jersey, for generous supplies of thiamin and vitamin B₆; to the Abbott Laboratories, North Chicago, for haliver oil; to the Pabst Brewing Company, Milwaukee, for yeast; to Wilson Laboratories, Chicago, for liver extract; and to Allied Mills Inc., Peoria, Illinois, for soybean oil.

Manuscript received 12 August 1940.