QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Waisman, H. A. Articles by Elvehjem, C. A. Search for Related Content PubMed Articles by Waisman, H. A. Articles by Elvehjem, C. A.

Multiple Deficiencies in the Modified Goldberger Diet as Demonstrated with Chicks¹

Two Figures>

Department of Biochemistry, College of Agriculture, University of Wisconsin, Madison

The limitations of the modified Goldberger ration have been determined with the aid of chicks and supplementation with various vitamins. Thiamin exerts no effect on growth, but riboflavin has been shown to give definite growth responses. Nicotinic acid was found to give variable responses in growth at levels below 20 mg. per 100 gm. of ration. Vitamin B₆ alone did not increase growth over the basal, but when added to a liver fraction which furnished additional factors, a definite response was obtained. The basal ration was found to be low in pantothenic acid and factor U. It has been demonstrated that additional factors other than the known members of the vitamin B complex are necessary for optimum growth of chicks fed the modified Goldberger diet. Various levels of animal tissues have been found to give good growth when used as supplements to the basal diet. There is no significant change in the blood picture of the chicks other than a reduced hemoglobin content of the blood when on the basal diet.

Manuscript received 15 July 1940.