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The Cause of the Laxative Action of Bran

(From the Department of Internal Medicine, Medical School, University of Michigan, Ann Arbor.)

1. A method of studying the fecal output of the rat is described. In the rat:

2. Bran acts as a laxative in a quantitative fashion—increasing amounts of bran produce increasing weights of feces.

3. Phytin-free bran has lost none of the laxative qualities of bran.

4. The ash of bran and the phytin contained in bran are not laxative in the quantities in which they are contained in bran. Bran ash fed separately may be slightly laxative in high concentrations.

5. Bran owes its laxative action to the crude fiber and pentosans which it contains.