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The Use of Isolated Radiations in Experiments with the Rat

I. The Effect of Infra-Red Radiation on the Growth of the Rachitic Rat

(From the Department of Pedicatics; Yale University, New Haven, Conn., The University of Rochester, Rochester N. Y., and Johns Hopkins University, Baltimore, Md.)

1. A 10 minutes daily exposure to near infra-red radiation (720–1120 mµ) total energy value (0.122 gm. cal/min/cm²) from a carbon are lamp, will stimulate growth in rachitic rats and prolong their period of survival on the rickets-producing diet.

2. The effect of infra-red radiation on the rats is different from that of ultra-violet since the animals receive no protection against the disease.

3. An increase in air temperature during summer conditons of experiment will depress the vitality of the rats, and make them less likely to respond to treatment with infra-red radiation.

4. Given in conjunction with ultra-violet, infra-red radiation also stimulates growth, to some extent, in rats fed on a standard rickets-producing diet.

In conclusion may warm thanks are due to Dr. E. A. Park for his constant support and helpful criticism throughout the course of these experiments; also to my assistant Miss Ruth Teasdale for skilled and conscientious help in tedious routine work. I should like also to thank the anonymous donor of the Gift Fund of Yale University whose generosity has defrayed the cost of this research. My thanks also are due to Dean G. H. Whipple for the hospitality of the laboratories in the Medical School of the Universityof Rochester, where these expeinents have been carried out.

Manuscript received 10 June 1929.