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Journal of Nutrition Vol. 19 No. 6 June 1940, pp. 547-554
Copyright © 1940 by American Society for Nutrition
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The Prevention of Nutritional Muscular Dystrophy in Guinea Pigs with Vitamin E1

Nobuko Shimotori, Gladys A. Emerson and Herbert M. Evans

Institute of Experimental Biology, University of California, Berkeley

Wheat germ, wheat germ oil, and alpha tocopherol protect against the nutritional muscular dystrophy that can be produced in guinea pigs reared on the Madsen, McCay and Maynard cod liver oil-containing diet. It would, therefore, seem apparent that when the vitamin B complex is adequately supplied, vitamin E is the specific factor preventing nutritional muscular dystrophy.

1 Aided by grants from the Research Board and the Department of Agriculture of the University of California, the Rockefeller Foundation and Merck and Company, Rahway, New Jersey. The following materials were generously contributed: alpha-tocopherol by Merck and Company, Rahway, New Jersey; wheat germ by General Mills, Inc. Assistance was rendered by the Works Progress Administration, Official Project No. 65-1-08-62, Unit A-5.

Manuscript received 16 January 1940.




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