The Influence of a Carcinogenic Compound on the Hepatic Storage of Vitamins
Alfred Goerner and
M. Margaret Goerner
Department of Biological Chemistry, Long Island College of Medicine, Brooklyn, New York
1. Intraperitoneal injections of 1,2,5,6-dibenzanthracene decreasedthe hepatic storage of vitamin A but not that of vitamins Cor D. No vitamin A could be detected, however, in the urineexcreted by the treated animals.
2. The inhibition of growthcaused by dibenzanthracene in youngrats was paralleled by thedecrease in hepatic vitamin A.
3. No effect on the calcificationof osseous tissues was observedin young rats treated with thehydrocarbon.