Journal of Nutrition

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Journal of Nutrition Vol. 18 No. 5 November 1939, pp. 441-446
Copyright © 1939 by American Society for Nutrition
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The Influence of a Carcinogenic Compound on the Hepatic Storage of Vitamins

Alfred Goerner and M. Margaret Goerner

Department of Biological Chemistry, Long Island College of Medicine, Brooklyn, New York

1. Intraperitoneal injections of 1,2,5,6-dibenzanthracene decreased the hepatic storage of vitamin A but not that of vitamins C or D. No vitamin A could be detected, however, in the urine excreted by the treated animals.
2. The inhibition of growth caused by dibenzanthracene in young rats was paralleled by the decrease in hepatic vitamin A.
3. No effect on the calcification of osseous tissues was observed in young rats treated with the hydrocarbon.


Manuscript received 12 June 1939.





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