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Vitamin B₁ Content of Human Milk as Affected by Ingestion of Thiamin Chloride¹

Laboratory of Home Economics, University of California, Berkeley

Two healthy young women taking diets of widely different vitamin B₁ content were found to secrete milk of similarly different vitamin B₁ potency, 32 and 11 µg. per 100 gm.

When each of these subjects took 5 mg. of crystalline thiamin chloride daily during a period of 1 month no increase occurred in the vitamin B₁ of the milk of the higher potency but some rise was seen in that of lower potency. The new level of the latter milk was 20 µg. per 100 gm.

The first subject then took 10 mg. and the second 14.2 mg. thiamin chloride for a month. The new levels were 25 and 25 µg. per 100 gm.

Three assays of market samples of cow's milk showed 27, 30 and 32 µg. per 100 gm.

It is concluded that the level of vitamin B₁ in human milk is controlled in the lower brackets by the vitamin B₁ content of the diet but that as in cow's milk a maximum level exists above which the vitamin content cannot be raised even by massive doses of thiamin chloride. This maximum level appears to be the same in human and cow's milk, 25 to 32 µg. per 100 gm. of milk.

Manuscript received 17 April 1939.

This article has been cited by other articles:

				R. M. WILDER, H. C. BROWNE, and H. R. BUTT DISEASES OF METABOLISM AND NUTRITION: REVIEW OF CERTAIN RECENT CONTRIBUTIONS Arch Intern Med, February 1, 1940; 65(2): 390 - 460. [Abstract] [PDF]