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The Acid Soluble Phosphorus Content of Muscle of Rats Under Various Diet Modifications¹

One Figure

Department of Physiology, College of Medicine, University of Illinois, Chicago

1. The acid soluble phosphorus content of skeletal muscle of white rats in the third colony on all dietary modifications used showed a marked increase from 13 weeks to 43 weeks.

2. The high phosphorus diet produced the greatest increase. The other diets retarded the increase when compared to the normal diet, but the differences were not statistically significant.

3. From 43 to 65 weeks there was a definite decrease in acid-soluble phosphorus content which was most pronounced on the normal diet and definitely retarded in all other groups. Normal diet plus growth hormone prevented the decline practically completely. Again differences were not statistically significant except in this one instance.

4. In the fourth colony there was found an increase in the acid soluble phosphorus content of muscle up to 17 weeks, which was retarded in this case by the high phosphorus diet. From 17 to 25 weeks the decrease found on the normal diet was retarded by high phosphorus diet.

Manuscript received 12 September 1938.