QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Haldi, J. Articles by Wynn, W. Search for Related Content PubMed Articles by Haldi, J. Articles by Wynn, W.

Comparative Effects of a High Glucose and a High Fructose Diet on Activity, Body Weight and Various Constituents of the Liver and Body of the Albino Rat Exercising at Will¹

Two Figures

T. T. Fishburne Laboratory of Physiology, Emory University, Georgia

Spontaneous activity, gain in weight and various constituents of the body and liver have been studied on rats maintained on diets that were identical except that one contained 68% glucose, one the same percentage of fructose and another a mixture of the two sugars in equal parts. The animals were kept in cages allowing free access to a wheel provided with counters.

There were no significant differences in the gain in weight on the three diets.

Spontaneous activity was greatest on the glucose ration, least on fructose and intermediate on the mixture.

There was but a small difference in the body fat of the glucose and fructose-fed rats of these experiments whereas in the non-exercising experiments reported in the previous paper, there was considerably more body fat on the glucose ration. The fat content of the body of both the glucose and fructosefed animals was considerably less than in the corresponding non-exercise experiments. These differences are accounted for by the activity of the exercising animals. It is concluded that the energy required for the exercise was supplied for the most part at the expense of body fat.

The percentage nitrogen and glycogen of the body was the same on the glucose and fructose rations.

The liver was appreciably larger on the fructose than on the glucose diet.

The percentage nitrogen of the liver was the same on the two diets, and the percentage glycogen the same on glucose and fructose but higher on a mixture of the sugars; the percentage fat was higher on the glucose than on the fructose diet.

Manuscript received 25 April 1938.