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The Effect of Prolonged Exposure to Low Temperature on the Basal Metabolism of the Rat

Departments of Physiology and Materia Medica, University of Buffalo, Buffalo

Exposure of the albino rat to low temperatures (7 to 12°C.) for the major portion of each day, for 15-, 30- or 60-day periods: 1) increases basal metabolic rate as measured at thermal neutrality, 11 to 16%; this increase, per unit of weight, reaches a maximum and sustained level between the fifteenth and thirtieth day; per unit of body surface the effect is slightly less, though still statistically significant; 2) increases body temperature; correction for this still leaves a significant increase in metabolic rate; 3) retards gain in weight; 4) does not affect the respiratory quotient.