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Effect of Diets Containing Fats of Various Degrees of Unsaturation on the Serum Lipids in Rats¹

Departments of Pediatrics and Botany, University of Minnesota

1. When rats were reared on diets containing fats of various degrees of unsaturation the iodine numbers of the total lipids of the serum tended to vary directly with the iodine number of the dietary fats.

2. The values for the total lipids were found to vary inversely with the degree of unsaturation of the serum lipids.

3. The results indicate the possibility of a selective retention of the unsaturated fatty acids of the blood.

4. These data indicate that the character of the diet must be taken into consideration in the interpretation of metabolic studies involving the serum lipids, particularly as regards the degree of unsaturation of the fatty acids.

5. The results show that a positive correlation exists between the degree of unsaturation of food fat, depot fat and the blood fat.

² Aided by grants from the Medical Research Fund, Graduate School, University of Minnesota and from the National Live Stock and Meat Board.

Manuscript received 19 July 1937.