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A New Salt Mixture for Use in Experimental Diets1

Rebecca B. Hubbell, Lafayette B. Mendel2 and Alfred J. Wakeman

Biochemical Laboratory, Connecticut Agricultural Experiment Station, and Laboratory of Physiological Chemistry, Yale University, New Haven

A new salt mixture has been described in which the proportion of calcium to other constituents has been greatly increased. This preparation, made by mixing dry salts, may be used at the level of 2% in many diets of purified foods which usually require 4% Osborne and Mendel salts.

In experiments designed to compare the two salt mixtures during a selected period of active growth, from 60 to 200 gm. body weight, at a rate in excess of 5 gm. a day, adequate calcification of the femora has resulted with an average daily intake of approximately 50 mg. calcium and 35 mg. phosphorus.


1 The expenses of this investigation were shared by the Connecticut Agricultural Experiment Station and the Carnegie Institution of Washington.

2 Part of the experimental work reported in this paper was completed after the death of Professor Mendel. Prof. Arthur H. Smith has generously advised us during much of the investigation, and it is with pleasure that we acknowledge his cooperation.

Manuscript received 27 February 1937.


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