QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Online Supplemental Material Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Miller, M. R. Articles by Carter, C. G. Search for Related Content PubMed PubMed Citation Articles by Miller, M. R. Articles by Carter, C. G.

---

Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions

Increased Elongase and Desaturase Gene Expression with Stearidonic Acid Enriched Diet Does Not Enhance Long-Chain (n-3) Content of Seawater Atlantic Salmon (Salmo salar L.)^1–3,

⁴ National Centre for Marine Conservation and Resource Sustainability, University of Tasmania, Launceston, Tasmania 7250, Australia and ⁵ Commonwealth Scientific and Industrial Research Organisation (CSIRO) Food Futures Flagship and Division of Marine and Atmospheric Research, Hobart, Tasmania 7001, Australia

^* To whom correspondence should be addressed. E-mail: millerm{at}crop.cri.nz.

Atlantic salmon (Salmo salar L.) can produce (n-3) long-chain (LC)-PUFA when fed biosynthetic precursors. This has potential for developing sustainable aquafeeds. Echium oil (EO) is rich in stearidonic acid [SDA; 18:4(n-3)] and bypasses the initial 6 desaturase (FAD6) step in the (n-3) LC-PUFA biosynthetic pathway. EO was fed to seawater Atlantic salmon for 12 wk and compared with fish fed a diet containing canola oil (CO), a source of -linolenic acid [ALA; 18:3(n-3)] or fish oil (FO) that provides (n-3) LC-PUFA. Fatty acid (FA) composition of liver, white muscle, and whole fish was measured to show whether dietary precursors were endogenously biosynthesized to LC-PUFA. Gene expression of liver FA elongase and FAD5 was upregulated in EO fish compared with FO fish. Furthermore, dietary precursors affected the FA concentrations of direct biosynthetic products in all tissues. The increased gene expression in the EO fish was reflected by an increased FA concentration of eicosapentaenoic acid [20:5(n-3)] in the liver compared with the CO fish. However, the high concentrations of (n-3) LC-PUFA found in seawater Atlantic salmon fed diets rich in FO were not attained via biosynthesis from precursors (ALA or SDA) in diets.

This article has been cited by other articles:

				D. L. Palmquist Omega-3 Fatty Acids in Metabolism, Health, and Nutrition and for Modified Animal Product Foods Professional Animal Scientist, June 1, 2009; 25(3): 207 - 249. [Abstract] [PDF]