QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Esmaillzadeh, A. Articles by Willett, W. C. Search for Related Content PubMed PubMed Citation Articles by Esmaillzadeh, A. Articles by Willett, W. C.

---

Nutritional Epidemiology

Dietary Patterns and Markers of Systemic Inflammation among Iranian Women¹

² Department of Nutrition, School of Health and ³ Nutrition Research Center, Isfahan University of Medical Sciences, Isfahan PO Box 81745, Iran; ⁴ Department of Human Nutrition, School of Nutrition and Food Science and ⁵ School of Public Health, Shaheed Beheshti University of Medical Sciences, Tehran PO Box 19826-19573, Iran; and ⁶ Department of Nutrition and ⁷ Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115

^* To whom correspondence should be addressed. E-mail: esmaillzadeh{at}hlth.mui.ac.ir.

Few studies have examined the contribution of major dietary patterns to markers of systemic inflammation. This study was conducted to evaluate the association of major dietary patterns with markers of systemic inflammation among Iranian women. In a cross-sectional study of 486 healthy women aged 40–60 y, we assessed usual dietary intakes by means of an FFQ. Dietary patterns were identified by factor analysis. Anthropometric measurements were made and blood samples from fasting were taken for measuring inflammatory markers. The healthy pattern (high in fruits, vegetables, tomato, poultry, legumes, tea, fruit juices, and whole grains) was inversely related to plasma concentrations of C-reactive protein (CRP) (ß = –0.09, P < 0.001), E-selectin (ß = –0.07, P < 0.05), and soluble vascular cell adhesion molecule-1 (sVCAM-1) (ß = –0.08, P < 0.001) after control for potential confounders; with further adjustment for BMI and waist circumference (WC), the associations remained significant for CRP (ß = –0.05, P < 0.05) and sVCAM-1 (ß = –0.04, P < 0.05). In contrast, the western pattern score (high in refined grains, red meat, butter, processed meat, high-fat dairy, sweets and desserts, pizza, potato, eggs, hydrogenated fats, and soft drinks) was positively related to CRP (ß = 0.08, P < 0.001), serum amyloid A (SAA) (ß = 0.11, P < 0.05), IL-6 (ß = 0.09, P < 0.001), soluble intercellular adhesion molecule-1 (ß = 0.05, P < 0.05), and sVCAM-1 concentrations (ß = 0.07, P < 0.05). However, after additional control for BMI and WC, the associations remained significant only for SAA (ß = 0.06, P < 0.05) and IL-6 (ß = 0.07, P < 0.001). The traditional dietary pattern (high in refined grains, potato, tea, whole grains, hydrogenated fats, legumes, and casserole) was positively associated with the plasma IL-6 concentration (ß = 0.04, P < 0.05) when we controlled for confounders including BMI and WC. The findings suggest an independent association between major dietary patterns and plasma concentrations of markers of inflammation.

This article has been cited by other articles:

				S. Eilat-Adar, M. Mete, E. D. Nobmann, J. Xu, R. R. Fabsitz, S. O. E. Ebbesson, and B. V. Howard Dietary Patterns are Linked to Cardiovascular Risk Factors but Not to Inflammatory Markers in Alaska Eskimos J. Nutr., December 1, 2009; 139(12): 2322 - 2328. [Abstract] [Full Text] [PDF]

				P. P. Cavicchia, S. E. Steck, T. G. Hurley, J. R. Hussey, Y. Ma, I. S. Ockene, and J. R. Hebert A New Dietary Inflammatory Index Predicts Interval Changes in Serum High-Sensitivity C-Reactive Protein J. Nutr., December 1, 2009; 139(12): 2365 - 2372. [Abstract] [Full Text] [PDF]

				D. R Jacobs Jr, D. Sluik, M. H Rokling-Andersen, S. A Anderssen, and C. A Drevon Association of 1-y changes in diet pattern with cardiovascular disease risk factors and adipokines: results from the 1-y randomized Oslo Diet and Exercise Study Am. J. Clinical Nutrition, February 1, 2009; 89(2): 509 - 517. [Abstract] [Full Text] [PDF]

				L. Azadbakht and A. Esmaillzadeh Red Meat Intake Is Associated with Metabolic Syndrome and the Plasma C-Reactive Protein Concentration in Women J. Nutr., February 1, 2009; 139(2): 335 - 339. [Abstract] [Full Text] [PDF]

				A. Esmaillzadeh and L. Azadbakht Home use of vegetable oils, markers of systemic inflammation, and endothelial dysfunction among women Am. J. Clinical Nutrition, October 1, 2008; 88(4): 913 - 921. [Abstract] [Full Text] [PDF]

				A. Esmaillzadeh and L. Azadbakht Food Intake Patterns May Explain the High Prevalence of Cardiovascular Risk Factors among Iranian Women J. Nutr., August 1, 2008; 138(8): 1469 - 1475. [Abstract] [Full Text] [PDF]

				A. Nanri, D. Yoshida, T. Yamaji, T. Mizoue, R. Takayanagi, and S. Kono Dietary patterns and C-reactive protein in Japanese men and women Am. J. Clinical Nutrition, May 1, 2008; 87(5): 1488 - 1496. [Abstract] [Full Text] [PDF]

				A. Esmaillzadeh and L. Azadbakht Major Dietary Patterns in Relation to General Obesity and Central Adiposity among Iranian Women J. Nutr., February 1, 2008; 138(2): 358 - 363. [Abstract] [Full Text] [PDF]