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© 2007 American Society for Nutrition J. Nutr. 137:2503S-2506S, November 2007

Inulin and Oligofructose: Health Benefits and Claims-A Critical Review

Prebiotic Capacity of Inulin-Type Fructans1–3,

Sofia Kolida and Glenn R. Gibson*

Food Microbial Sciences Unit, Department of Food Biosciences, The University of Reading, Reading, UK

* To whom correspondence should be addressed. E-mail: g.r.gibson{at}reading.ac.uk.

The human gut microbiota plays a significant role in human health through its ability to digest food ingredients and manufacture metabolites. This can be positive or negative for host welfare. Moreover, the microflora plays an active role in host defense whereby colonization resistance affords protection against pathogens. Prebiotics are nondigestible food ingredients that target beneficial components of the gut microflora (mainly colonic), particularly the bifidobacteria. In vitro and in vivo evidence has accumulated to confirm the prebiotic effects of inulin-derived fructans.






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