QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Canene-Adams, K. Articles by Erdman, J. W. Search for Related Content PubMed PubMed Citation Articles by Canene-Adams, K. Articles by Erdman, J. W., Jr

---

Symposium: Relative Bioactivity of Functional Foods and Related Dietary Supplements

The Tomato As a Functional Food^1,2

Department of Food Science and Human Nutrition and the Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801

³To whom correspondence should be addressed. E-mail: jwerdman{at}uiuc.edu.

Tomatoes are the fourth most commonly consumed fresh vegetable and the most frequently consumed canned vegetable in the American diet. There is emerging epidemiology data supporting the connection between increased tomato consumption and reduced risk for both cardiovascular disease and prostate cancer. Here we will summarize the nutrient and the phytochemical content of tomatoes and tomato products, and how these bioactive components might act together to modulate disease development. Recent animal studies have investigated tomatoes, lycopene, and prostate cancer using the N-methyl-N-nitrosourea and Dunning rat models. These animal studies also suggest that diets containing tomatoes may decrease the risk or the progression of prostate cancer. Due to the frequency and the extent of tomato consumption, the supporting epidemiological and animal data, which connect increased intakes with decreased cancer and cardiovascular disease risk, tomato’s role in the American diet is of undeniable importance as part of a healthy diet.

KEY WORDS: • tomato • lycopene • prostate cancer • cardiovascular disease

This article has been cited by other articles:

				S. Devaraj, S. Mathur, A. Basu, H. H. Aung, V. T. Vasu, S. Meyers, and I. Jialal A Dose-Response Study on the Effects of Purified Lycopene Supplementation on Biomarkers of Oxidative Stress J. Am. Coll. Nutr., April 1, 2008; 27(2): 267 - 273. [Abstract] [Full Text] [PDF]

				J. P. Mills, P. W. Simon, and S. A. Tanumihardjo {beta}-Carotene from Red Carrot Maintains Vitamin A Status, but Lycopene Bioavailability Is Lower Relative to Tomato Paste in Mongolian Gerbils J. Nutr., June 1, 2007; 137(6): 1395 - 1400. [Abstract] [Full Text] [PDF]

				K. Canene-Adams, B. L. Lindshield, S. Wang, E. H. Jeffery, S. K. Clinton, and J. W. Erdman Jr. Combinations of Tomato and Broccoli Enhance Antitumor Activity in Dunning R3327-H Prostate Adenocarcinomas Cancer Res., January 15, 2007; 67(2): 836 - 843. [Abstract] [Full Text] [PDF]

				H. J. Thompson, J. Heimendinger, A. Diker, C. O'Neill, A. Haegele, B. Meinecke, P. Wolfe, S. Sedlacek, Z. Zhu, and W. Jiang Dietary Botanical Diversity Affects the Reduction of Oxidative Biomarkers in Women due to High Vegetable and Fruit Intake J. Nutr., August 1, 2006; 136(8): 2207 - 2212. [Abstract] [Full Text] [PDF]

				B. van der Rest, S. Danoun, A.-M. Boudet, and S. F. Rochange Down-regulation of cinnamoyl-CoA reductase in tomato (Solanum lycopersicum L.) induces dramatic changes in soluble phenolic pools J. Exp. Bot., March 1, 2006; 57(6): 1399 - 1411. [Abstract] [Full Text] [PDF]