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Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA
2To whom correspondence should be addressed. E-mail: Email: ghotamis{at}hsph.harvard.edu.
Fatty acid binding proteins (FABPs) are members of a highly conserved family of proteins with the task of protecting a cell’s delicate lipid balance. Yet they fail when faced with metabolic or inflammatory stress, turning the cytosol into an inhospitable environment with less than ideal outcomes. This review will focus on how FABPs direct lipid traffic and simultaneously control inflammatory and metabolic pathways under the pressures of the Metabolic Syndrome.
KEY WORDS: • fatty acid binding protein (FABP) • Metabolic Syndrome • inflammation • obesity • insulin resistance
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