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© 2004 The American Society for Nutritional Sciences J. Nutr. 134:2729-2732, October 2004

Issues and Opinions

Metabolomics in the Opening Decade of the 21st Century: Building the Roads to Individualized Health

J. B. German, D. E. Bauman, D. G. Burrin, M. L. Failla, H. C. Freake1, J. C. King, S. Klein, J. A. Milner, G. H. Pelto, K. M. Rasmussen and S. H. Zeisel

American Society for Nutritional Sciences Long Range Planning Committee

1To whom correspondence should be addressed. E-mail: hedley.freake{at}uconn.edu.

It is rapidly becoming possible to measure hundreds or thousands of metabolites in small samples of biological fluids or tissues. This makes it possible to assess the metabolic component of nutritional phenotypes and will allow individualized dietary recommendations. ASNS has to take action to ensure that appropriate technologies are developed and that metabolic databases are constructed with the right inputs and organization. The relations between diet and metabolomic profiles and between those profiles and health and disease must be established. ASNS also should consider the social implications of these advances and plan for their appropriate utilization.




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