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Supplement: 11th International Symposium on Trace Elements in Man and Animals

Assessment of the Trace Element Status of Individuals and Populations: The Example of Zinc and Copper ^{1 ,2}

Christine Hotz^*, Nicola M. Lowe, Magdalena Araya^** and Kenneth H. Brown^,3

^* Centro de Investigación en Nutrición y Salud, Instituto Nacional de Salud Publica, Cuernavaca, Morelos, Mexico, Department of Nutritional Sciences, University of Central Lancashire, Preston PR1 2HE, United Kingdom, ^** Instituto de Nutrición y Technologia de Alimentos, Santiago, Chile and Program in International Nutrition and Department of Nutrition, University of California, Davis, CA

³ To whom correspondence should be addressed. E-mail: khbrown{at}ucdavis.edu.

This paper describes the proceedings of a workshop that was convened at the 11th International Symposium on Trace Elements in Man and Animals (TEMA-11) symposium to review recent advances concerning the assessment of the trace element status of individuals and populations, using zinc and copper as the primary examples to illustrate basic principles and recent advances in assessment methods. The workshop was initiated with a brief review of the importance of zinc nutriture for human health and a discussion of the likely common occurrence of zinc deficiency worldwide. This overview was followed by presentations on selected issues concerning the assessment of zinc status, with particular attention devoted to dietary assessment techniques, the use of isotopic tracers to assess zinc homeostasis and the relationship of these methods to biochemical indicators of zinc status. Because relatively little information is available on zinc toxicity, the discussion concerning the definition of excess intake of trace elements focused primarily on recent work concerning risk assessment of copper toxicity.

KEY WORDS: • zinc • copper • trace elements • nutritional assessment • toxicity

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