![[Feedback]](/icons/banner/feedbackACT.gif){kind=icon}
![[For Subscribers]](/icons/banner/subscriberACT.gif){kind=icon}
![[Archive]](/icons/banner/archiveACT.gif){kind=icon}
![[Search]](/icons/banner/searchACT.gif){kind=icon}
![[Contents]](/icons/banner/tocACT.gif){kind=icon}
|
|
|
|
|
||
,2
* Department of Health Promotion and Preventive Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan;
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya 464-8681, Japan;
** Department of Health and Nutrition, Nagoya Bunri University School of Health and Human Life, Inazawa 492-8520, Japan;
Nagoya City School of Nutrition, Nagoya 467-0011, Japan;
Nagoya City University School of Nursing, Nagoya 467-8601, Japan;
Department of General Medicine, Nagoya University Hospital, Nagoya 466-8560, Japan;
# Department of Occupational Health Economics, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan; and
Aichi Prefectural Dietetic Association, Nagoya 462-0845, Japan
2To whom correspondence should be addressed. E-mail: kkuriki{at}aichi-cc.jp.
A cross-sectional study was conducteded to clarify the associations of lifestyle factors (habitual exercise, alcohol intake and smoking habit) and plasma fatty acid (FA) concentrations as biomarkers of dietary FA intakes. We collected 7-d weighed diet records, lifestyle information and blood samples from 15 male and 79 female Japanese dietitians, and estimated dietary FA intakes and analyzed plasma FA concentrations. Plasma concentrations of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and (n-3) highly unsaturated FA (HUFA) derived from marine foods, but not linoleic and 
-linolenic acid from plant origins, demonstrated positive correlations with dietary intakes (r = 0.303–0.602, P < 0.05) in both genders. Multiple linear regression analyses adjusted for age, BMI, total energy intake, fat (or respective FA) consumption and lifestyle factors showed that dietary intakes of EPA, DHA and (n-3) HUFA were positively associated with age in men (P < 0.05) and negatively associated with BMI in women [P < 0.01 for DHA and (n-3) HUFA]. The plasma concentrations of EPA, DHA and (n-3) HUFA in women were found to be positively associated with age and marine oil (or respective FA) intake (P < 0.01), and negatively associated with total energy intake [P < 0.05 for EPA and (n-3) HUFA]. Lifestyle factors were not associated with dietary FA intakes and plasma FA concentrations. These findings suggest that the plasma concentrations of EPA, DHA and (n-3) HUFA might be useful biomarkers for the assessment of relative FA intakes without considering associations with habitual exercise, alcohol intake and smoking habit.
KEY WORDS: • biomarker • diet record • fatty acid • lifestyle • plasma concentration
This article has been cited by other articles:
|
|
 |
|
  Y. Miyake, S. Sasaki, K. Tanaka, Y. Ohya, S. Miyamoto, I. Matsunaga, T. Yoshida, Y. Hirota, H. Oda, and the Osaka Maternal and Child Health Study Group Fish and Fat Intake and Prevalence of Allergic Rhinitis in Japanese Females: the Osaka Maternal and Child Health Study J. Am. Coll. Nutr., June 1, 2007; 26(3): 279 - 287. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. A Beydoun, J. S Kaufman, J. A Satia, W. Rosamond, and A. R Folsom Plasma n-3 fatty acids and the risk of cognitive decline in older adults: the Atherosclerosis Risk in Communities Study Am. J. Clinical Nutrition, April 1, 2007; 85(4): 1103 - 1111. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Philibert, C. Vanier, N. Abdelouahab, H. M. Chan, and D. Mergler Fish intake and serum fatty acid profiles from freshwater fish Am. J. Clinical Nutrition, December 1, 2006; 84(6): 1299 - 1307. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H.-K. Kim, M. Della-Fera, J. Lin, and C. A. Baile Docosahexaenoic Acid Inhibits Adipocyte Differentiation and Induces Apoptosis in 3T3-L1 Preadipocytes J. Nutr., December 1, 2006; 136(12): 2965 - 2969. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Kuriki, K. Wakai, K. Hirose, K. Matsuo, H. Ito, T. Suzuki, T. Saito, Y. Kanemitsu, T. Hirai, T. Kato, et al. Risk of colorectal cancer is linked to erythrocyte compositions of Fatty acids as biomarkers for dietary intakes of fish, fat, and Fatty acids. Cancer Epidemiol. Biomarkers Prev., October 1, 2006; 15(10): 1791 - 1798. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Masood, K. D. Stark, and N. Salem Jr. A simplified and efficient method for the analysis of fatty acid methyl esters suitable for large clinical studies J. Lipid Res., October 1, 2005; 46(10): 2299 - 2305. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Baylin, M. K. Kim, A. Donovan-Palmer, X. Siles, L. Dougherty, P. Tocco, and H. Campos Fasting Whole Blood as a Biomarker of Essential Fatty Acid Intake in Epidemiologic Studies: Comparison with Adipose Tissue and Plasma Am. J. Epidemiol., August 15, 2005; 162(4): 373 - 381. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. D. Stark, S. Beblo, M. Murthy, M. Buda-Abela, J. Janisse, H. Rockett, J. E. Whitty, S. S. Martier, R. J. Sokol, J. H. Hannigan, et al. Comparison of bloodstream fatty acid composition from African-American women at gestation, delivery, and postpartum J. Lipid Res., March 1, 2005; 46(3): 516 - 525. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Kojima, K. Wakai, S. Tokudome, K. Suzuki, K. Tamakoshi, Y. Watanabe, M. Kawado, S. Hashimoto, N. Hayakawa, K. Ozasa, et al. Serum Levels of Polyunsaturated Fatty Acids and Risk of Colorectal Cancer: A Prospective Study Am. J. Epidemiol., March 1, 2005; 161(5): 462 - 471. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Denomme, K. D. Stark, and B. J. Holub Directly Quantitated Dietary (n-3) Fatty Acid Intakes of Pregnant Canadian Women Are Lower than Current Dietary Recommendations J. Nutr., February 1, 2005; 135(2): 206 - 211. [Abstract] [Full Text] [PDF]
|
|
