![[Feedback]](/icons/banner/feedbackACT.gif){kind=icon}
![[For Subscribers]](/icons/banner/subscriberACT.gif){kind=icon}
![[Archive]](/icons/banner/archiveACT.gif){kind=icon}
![[Search]](/icons/banner/searchACT.gif){kind=icon}
![[Contents]](/icons/banner/tocACT.gif){kind=icon}
|
|
|
|
|
||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Nutraceuticals and Functional Foods Institute, Laval University, Québec, Canada G1K 7P4;
* Lipid Research Center, CHUL Research Center, Québec, Canada G1V 4G2;
Québec Heart Institute, Laval Hospital Research Center, Québec, Canada G1V 4G5
6To whom correspondence should be addressed. E-mail: Nathalie.Bergeron{at}inaf.ulaval.ca.
We compared the effects of ad libitum consumption of a defined high complex carbohydrate (CHO) diet (% of energy: CHO, 58.3; fat, 25.8) vs. a defined high monounsaturated fatty acid (MUFA) diet (% of energy: CHO, 44.7; fat, 40.1; MUFA, 22.5) on LDL electrophoretic characteristics. Healthy men [n = 65; age, 37.5 ± 11.2 (mean ± SD) y; BMI, 29.2 ± 4.9 kg/m2] were randomly assigned to one of the two diets that they consumed for 6–7 wk. The high CHO diet significantly reduced body weight (-2%). The diet-induced reduction in plasma LDL cholesterol (C) levels in the high-CHO diet group was due mainly to concurrent reductions in the cholesterol content of small (<25.5 nm, P < 0.01) and medium-sized LDL (25.5–26.0 nm, P = 0.01). The high MUFA diet also reduced body weight, and LDL-C and LDL-apolipoprotein (apo)B levels, which were comparable to those in the high CHO group. The cholesterol levels of small LDL particles tended to be reduced (P = 0.24) in the high MUFA group (-12%), similar to changes in the high CHO group. These results suggest that, when associated with weight loss, ad libitum consumption of high CHO and high MUFA diets may be considered to be equally beneficial for the management of LDL-related atherogenic dyslipidemia. However, the high MUFA diet more favorably affected triglyceride levels, suggesting that it may be preferable to a high CHO diet in cardiovascular disease prevention.
KEY WORDS: • LDL peak particle diameter • low fat-high carbohydrate diet • high fat-high monounsaturated fatty acid diet • lipids
This article has been cited by other articles:
|
|
 |
|
  C. Wadsack, S. Tabano, A. Maier, U. Hiden, G. Alvino, V. Cozzi, M. Huttinger, W. J. Schneider, U. Lang, I. Cetin, et al. Intrauterine growth restriction is associated with alterations in placental lipoprotein receptors and maternal lipoprotein composition Am J Physiol Endocrinol Metab, February 1, 2007; 292(2): E476 - E484. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. M Krauss, P. J Blanche, R. S Rawlings, H. S Fernstrom, and P. T Williams Reply to EC Westman et al Am. J. Clinical Nutrition, December 1, 2006; 84(6): 1550 - 1550. [Full Text] [PDF]
|
|
|
|
|
|
R. M Krauss, P. J Blanche, R. S Rawlings, H. S Fernstrom, and P. T Williams Separate effects of reduced carbohydrate intake and weight loss on atherogenic dyslipidemia Am. J. Clinical Nutrition, May 1, 2006; 83(5): 1025 - 1031. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Desroches, W. R. Archer, M.-E. Paradis, O. Deriaz, P. Couture, J. Bergeron, N. Bergeron, and B. Lamarche Baseline Plasma C-Reactive Protein Concentrations Influence Lipid and Lipoprotein Responses to Low-Fat and High Monounsaturated Fatty Acid Diets in Healthy Men J. Nutr., April 1, 2006; 136(4): 1005 - 1011. [Abstract] [Full Text] [PDF]
|
|
