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© 2002 The American Society for Nutritional Sciences J. Nutr. 132:2435S-2439S, 2002


Supplement: Trans-HHS Workshop: Diet, DNA Methylation Processes and Health

DNA Methylation Database "MethDB": a User Guide1 ,2

Christoph Grunau3, Eric Renault and Gérard Roizes

Laboratoire de Séquences Répétées et Centromères Humains, Institut de Génétique Humaine, Montpellier, France

3To whom correspondence should be addressed. E-mail: christoph.grunau{at}methdb.de.

The DNA Methylation Database (MethDB; http://www.methdb.net) is a public database dedicated to DNA methylation. It attempts to store all data about DNA methylation in a common source. MethDB can be searched in different ways, ranging from a simple browse mode to detailed queries for sequence-specific DNA methylation profiles and patterns, total methylation content data or environmental conditions that can influence the methylation state of DNA. Currently, the database contains 2570 values for methylation content and 5278 methylation patterns and profiles for a total of 83 genes or loci. MethDB is an annotated database, and the scientific community is invited to submit their own data (submit{at}methdb.de).


KEY WORDS: • DNA methylation • MethDB • epigenetics • database • cancer • 5-methylcytosine




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