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Energy Metabolism Laboratory, The Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111 and * Department of Student Nutrition, Institute of Nutrition and Food Hygiene, Chinese Academy of Preventive Medicine, Beijing, China 100050
2To whom correspondence should be addressed. E-mail: mmccrory{at}hnrc.tufts.edu.
There is little information on the accuracy of simple body composition methods in non-Western populations. We determined the percentage of body fat (%BF) by isotope dilution [oxygen-18 (H218O) and deuterium oxide (2H2O)] and anthropometry in 71 healthy, urban Chinese adults aged 35–49 y [body mass index (BMI) 18–35 kg/m2]. The accuracy of several prediction equations for assessment of %BF from skinfold measurements was evaluated against %BF determined by H218O dilution. We also assessed the relationship between BMI and %BF, and the fat-free mass (FFM) hydration coefficient for our population. All skinfold equations yielded means within 
2%BF of H218O-derived %BF. However, on the basis of residual plot analysis and the 95% confidence interval (CI) for the mean difference between methods, the equations of Durnin and Womersley (for assessment of body density from skinfolds) coupled with that of Brozek et al. (for assessment of %BF from body density) provided the most valid assessment for individuals. In addition, the FFM hydration coefficient averaged 0.734 ± 0.002 (SEM), indicating that the usually assumed value of 0.732 is appropriate for this population. Finally, although BMI had high specificity (90%) for classifying individuals as having body fat within the normal range (<24%BF for men, and <35%BF for women), it had poor sensitivity (66%) for identifying individuals as having high body fat. We conclude that compared with H218O dilution, skinfold thickness can provide an accurate and reliable assessment of body composition in healthy Chinese adults. Furthermore, using the equation of Brozek et al. may be preferable to using Siri’s equation to predict %BF from body density in populations in which individuals have >30%BF.
KEY WORDS: • isotope dilution • anthropometry • body mass index • percentage of body fat • fat-free mass hydration coefficient
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