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© 2002 The American Society for Nutritional Sciences J. Nutr. 132:3130-3134, October 2002

Nutrient Requirements

Determination of Vitamin B-6 Estimated Average Requirement and Recommended Dietary Allowance for Children Aged 7–12 Years Using Vitamin B-6 Intake, Nutritional Status and Anthropometry1

Sue-Joan Chang2, Yi-Chia Huang*, Li-Ju Hsiao, Yi-Chun Lee and Shou-Ying Hsuen

Department of Biology, National Cheng Kung University, Tainan, Taiwan and * School of Nutrition, Chung Shan Medical University, Taichung, Taiwan

2To whom correspondence should be addressed. E-mail: sjchang{at}mail.ncku.edu.tw.

The Estimated Average Requirement (EAR) and Recommended Dietary Allowance (RDA) of vitamin B-6 for children were recently estimated by extrapolating from adult values because of limited available information. To determine vitamin B-6 requirements and provide recommendations for intakes, vitamin B-6 intake, nutritional status and anthropometry of 168 healthy children (79 boys and 89 girls) were studied in Tainan, Taiwan. Direct and indirect vitamin B-6 status indicators were measured in plasma, erythrocytes and urine. Anthropometric data of children in this study were similar to those of the first Nutrition and Health Survey in Taiwan (NAHSIT) conducted in 1993–1996. The plasma pyridoxal phosphate (PLP) concentration of each child was >=30 nmol/L, indicating an adequate vitamin B-6 status. Daily dietary vitamin B-6 intakes of boys and girls were 0.80 ± 0.16 and 0.74 ± 0.16 mg/d, respectively. Daily dietary vitamin B-6 intakes of children who had adequate urinary 4-pyridoxic acid (4-PA) (>3.0 µmol/L), erythrocyte alanine aminotransferase activity coefficient (EALT-AC) (<1.25) and aspartate aminotransferase activity coefficient (EAST-AC) (<1.8) were not different from those of children who had adequate plasma PLP, although the percentages of adequacy for urinary 4-PA, EALT-AC and EAST-AC ranged from 20 to 91%. Vitamin B-6 status indicators were strongly correlated with vitamin B-6 intake. Adequate values of PLP, EALT-AC, EAST-AC and urinary 4-PA were used to determine the EAR according to Dietary Reference Intake (DRI) committee methodology. We determined the vitamin B-6 EAR (RDA) for boys and girls aged 7–12 y to be 0.84 (1.01) and 0.75 (0.89) mg/d, respectively.

KEY WORDS: • vitamin B-6 • nutritional status • Estimated Average Requirement • Recommended Dietary Allowance • school children




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S.-J. Chang, L.-J. Hsiao, and S.-Y. Hsuen
Assessment of Vitamin B-6 Estimated Average Requirement and Recommended Dietary Allowance for Adolescents Aged 13-15 Years Using Vitamin B-6 Intake, Nutritional Status and Anthropometry
J. Nutr., October 1, 2003; 133(10): 3191 - 3194.
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