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(Journal of Nutrition. 2001;131:1605S-1609S.)
© 2001 The American Society for Nutritional Sciences

Supplement

Molecular Approaches to Studying Nutrient Metabolism and Function: An Array of Possibilities1 ,2

Kendal D. Hirschi*, Joel A. Kreps** and Karen K. Hirschi{dagger},3

Departments of * Pediatrics and {dagger} Molecular and Cellular Biology, Baylor College of Medicine, Children’s Nutrition Research Center, Houston, TX 77030 and ** Torrey Mesa Research Institute, Syngenta, San Diego CA 92121

3To whom correspondence should be addressed. E-mail: khirschi{at}bcm.tmc.edu

Genomics promises to revolutionize the study of nutrient function and requirements and, thereby, solidify the connection of this field to basic sciences, such as molecular genetics. In this short review, we address the general concepts and techniques used in high throughput measurements of gene expression. We also speculate on how these technologies can be used to further our understanding of basic metabolism and nutrient regulation of gene expression in developmental and pathological conditions.

KEY WORDS: • microarray • genomics • genotype • differential gene expression




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