QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Abia, R. Articles by Ruiz-Gutiérrez, V. Search for Related Content PubMed PubMed Citation Articles by Abia, R. Articles by Ruiz-Gutiérrez, V.

---

Article

The Metabolic Availability of Dietary Triacylglycerols from Two High Oleic Oils during the Postprandial Period Does Not Depend on the Amount of Oleic Acid Ingested by Healthy Men¹

Instituto de la Grasa, Consejo Superior de Investigaciones Cientificas, 41012 Sevilla, Spain and ^* Hospitales Universitarios Virgen del Rocío, 41013 Sevilla, Spain

²To whom correspondence and reprint requests should be addressed. E-mail: valruiz{at}cica.es.

Monounsaturated oils, virgin olive oil (VOO) and high oleic sunflower oil (HOSO) are suggested to have selective physiologic effects on humans in the fasting state. The aim of the study was to evaluate whether two oils with equal amounts of oleic acid but with different compositions of minor fatty acids and triacylglycerol molecular species (TAG) could produce different triacylglycerol-rich lipoprotein (TRL)-TAG responses in the postprandial state. Eight normolipidemic men consumed the following three meals in random order on separate occasions with 2 wk between meals: control meal, control meal plus VOO and control meal plus HOSO. Plasma total TAG and TRL-TAG were measured hourly for 7 h after ingestion. TAG and sn-2 positional fatty acids within TAG were analyzed in the TRL fraction. Plasma total TAG concentrations in response to the dietary oils did not differ. However, TRL triglyceridemia was significantly lower after VOO intake (P < 0.05). The molecular species in the TRL fraction returned toward basal levels more quickly (P < 0.05) after VOO than HOSO intake. 2-Positional fatty acid analysis demonstrated higher proportions of stearic and palmitic acids and a lower proportion of oleic acid (P < 0.05) in TRL-TAG derived from HOSO. This study shows that VOO intake results in attenuated postprandial TAG concentration and faster TRL-TAG disappearance from blood compared with HOSO, suggesting that the oleic acid content may not be the main factor affecting TAG metabolism. Minor fatty acids such as linoleic acid and the 2-positional distribution of saturated stearic and palmitic acids into the TAG molecule may be important determinants of postprandial lipemia in normolipidemic men.

KEY WORDS: • monounsaturated oils • triacylglycerol • postprandial • minor fatty acids • humans

This article has been cited by other articles:

				M. Foltz, J. Maljaars, E. A. H. Schuring, R. J. P. van der Wal, T. Boer, G. S. M. Duchateau, H. P. F. Peters, F. Stellaard, and A. A. Masclee Intragastric layering of lipids delays lipid absorption and increases plasma CCK but has minor effects on gastric emptying and appetite Am J Physiol Gastrointest Liver Physiol, May 1, 2009; 296(5): G982 - G991. [Abstract] [Full Text] [PDF]

				S. Lopez, B. Bermudez, Y. M. Pacheco, G. Lopez-Lluch, W. Moreda, J. Villar, R. Abia, and F. J. G. Muriana Dietary Oleic and Palmitic Acids Modulate the Ratio of Triacylglycerols to Cholesterol in Postprandial Triacylglycerol-Rich Lipoproteins in Men and Cell Viability and Cycling in Human Monocytes J. Nutr., September 1, 2007; 137(9): 1999 - 2005. [Abstract] [Full Text] [PDF]

				R. Cabello-Moruno, J. S. Perona, J. Osada, M. Garcia, and V. Ruiz-Gutierrez Modifications in Postprandial Triglyceride-Rich Lipoprotein Composition and Size after the Intake of Pomace Olive Oil J. Am. Coll. Nutr., February 1, 2007; 26(1): 24 - 31. [Abstract] [Full Text] [PDF]

				J. S. Perona, J. Martinez-Gonzalez, J. M. Sanchez-Dominguez, L. Badimon, and V. Ruiz-Gutierrez The Unsaponifiable Fraction of Virgin Olive Oil in Chylomicrons from Men Improves the Balance between Vasoprotective and Prothrombotic Factors Released by Endothelial Cells J. Nutr., December 1, 2004; 134(12): 3284 - 3289. [Abstract] [Full Text] [PDF]

				B. Metzler, R. Abia, M. Ahmad, F. Wernig, O. Pachinger, Y. Hu, and Q. Xu Activation of Heat Shock Transcription Factor 1 in Atherosclerosis Am. J. Pathol., May 1, 2003; 162(5): 1669 - 1676. [Abstract] [Full Text] [PDF]

				T. J. Tittelbach and R. D. Mattes Oral Stimulation Influences Postprandial Triacylglycerol Concentrations in Humans: Nutrient Specificity J. Am. Coll. Nutr., October 1, 2001; 20(5): 485 - 493. [Abstract] [Full Text] [PDF]