![[Feedback]](/icons/banner/feedbackACT.gif){kind=icon}
![[For Subscribers]](/icons/banner/subscriberACT.gif){kind=icon}
![[Archive]](/icons/banner/archiveACT.gif){kind=icon}
![[Search]](/icons/banner/searchACT.gif){kind=icon}
![[Contents]](/icons/banner/tocACT.gif){kind=icon}
|
|
|
|
|
||
Department of General and Environmental Physiology, University of Naples "FEDERICO II", Italy I-80134
2To whom correspondence should be addressed at Dipartimento di Fisiologia Generale ed Ambientale, Via Mezzocannone 8, I-80134, Napoli, Italy. Fax: +39-081-5426868. E-mail: susiossa{at}unina.it
Energy intake, utilization, and partitioning were determined in male Wistar rats from 25 to 180 d of age. Serum free triiodothyronine, leptin, and free fatty acid concentrations were also measured. Energy balance measurements allowed us to identify a period from 25 to 90 d, characterized by a rapid body growth rate and another from 90 to 180 d, during which body growth rate slowed. From 25 to 180 d, we found decreases in daily energy intake and expenditure, which were faster before 90 d. The first period was characterized by storage of lipid and protein. In the second period, protein deposition approached zero and the excess of ingested energy was entirely stored as fat, so that age-associated obesity began to develop. The inability of rats to maintain a stable body weight after the cessation of growth of lean body mass is not due to decreased resting metabolism but rather to a partial leptin resistance.
KEY WORDS: • energy balance measurements • resting metabolic rate • leptin • developing rats
This article has been cited by other articles:
|
|
 |
|
  C. Abe, K. Tanaka, C. Awazu, and H. Morita Impairment of vestibular-mediated cardiovascular response and motor coordination in rats born and reared under hypergravity Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2008; 295(1): R173 - R180. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Sanchez, T. Priego, M. Palou, A. Tobaruela, A. Palou, and C. Pico Oral Supplementation with Physiological Doses of Leptin During Lactation in Rats Improves Insulin Sensitivity and Affects Food Preferences Later in Life Endocrinology, February 1, 2008; 149(2): 733 - 740. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Alonso, M. Moreno, P. Ordonez, R. Fernandez, C. Perez, F. Diaz, A. Navarro, J. Tolivia, and C. Gonzalez Chronic Estradiol Treatment Improves Brain Homeostasis during Aging in Female Rats Endocrinology, January 1, 2008; 149(1): 57 - 72. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Alonso, R. Fernandez, M. Moreno, P. Ordonez, H. Gonzalez-Pardo, N. M. Conejo, F. Diaz, and C. Gonzalez Positive Effects of 17{beta}-Estradiol on Insulin Sensitivity in Aged Ovariectomized Female Rats. J. Gerontol. A Biol. Sci. Med. Sci., May 1, 2006; 61(5): 419 - 426. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Iossa, M. P. Mollica, L. Lionetti, R. Crescenzo, R. Tasso, and G. Liverini A Possible Link Between Skeletal Muscle Mitochondrial Efficiency and Age-Induced Insulin Resistance Diabetes, November 1, 2004; 53(11): 2861 - 2866. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. P. Mirand, M.-A. Arnal-Bagnard, L. Mosoni, Y. Faulconnier, J.-M. Chardigny, and Y. Chilliard Cis-9, Trans-11 and Trans-10, Cis-12 Conjugated Linoleic Acid Isomers Do Not Modify Body Composition in Adult Sedentary or Exercised Rats J. Nutr., September 1, 2004; 134(9): 2263 - 2269. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. A. Mastronardi, W. H. Yu, and S. M. McCann Resting and circadian release of nitric oxide is controlled by leptin in male rats PNAS, April 16, 2002; 99(8): 5721 - 5726. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Iossa, M. P. Mollica, L. Lionetti, R. Crescenzo, M. Botta, A. Barletta, and G. Liverini Acetyl-L-Carnitine Supplementation Differently Influences Nutrient Partitioning, Serum Leptin Concentration and Skeletal Muscle Mitochondrial Respiration in Young and Old Rats J. Nutr., April 1, 2002; 132(4): 636 - 642. [Abstract] [Full Text] [PDF]
|
|
