![[Feedback]](/icons/banner/feedbackACT.gif){kind=icon}
![[For Subscribers]](/icons/banner/subscriberACT.gif){kind=icon}
![[Archive]](/icons/banner/archiveACT.gif){kind=icon}
![[Search]](/icons/banner/searchACT.gif){kind=icon}
![[Contents]](/icons/banner/tocACT.gif){kind=icon}
|
|
|
|
|
||
Manuscript received 27 October 1997. Initial reviews completed 24 November 1997. Revision accepted 4 February 1998.
Nutritional Science Center, Bioscience Laboratories, Meiji Seika Kaisha, Saitama 350-0289, Japan and * Department of Molecular Nutrition, Faculty of Nutritional Science, Kagawa Nutrition University, Saitama 350-0288, Japan
Previously, we confirmed that dietary fructooligosaccharides (FOS) increase calcium absorption in rats. In this study, we examined the influence of FOS feeding on the concentration of calbindin-D9k of several intestinal segments in rats. Rats in the control group were fed a diet without FOS. Rats in the other two groups were fed the diet containing FOS at either 50 or 100 g/kg for 10 d and subjected to a calcium absorption study. On the final day of feeding, the rats were killed and the entire intestine was removed. The intestinal mucosa was collected from four segments, i.e., the proximal and distal segments of the small intestine, the cecum and the colorectum, respectively. The apparent absorption of calcium increased dose dependently (r = 0.9256, P < 0.0001). Significant positive correlations between apparent calcium absorption and the relative amounts of calbindin in both large intestinal segments were observed (cecum, r = 0.8956, P = 0.0011; colorectum, r = 0.8828, P = 0.0016). Also, significant negative correlations between apparent calcium absorption and the relative amounts of calbindin-D9k in both small intestinal segments were observed (proximal, r = 
0.7149, P = 0.0304; distal, r = 0.8740, P = 0.0021). In conclusion, FOS feeding increases levels of calbindin-D9k in the large intestine, but decreases those in the small intestine. Moreover, these results suggest that part of the stimulatory effect of fructooligosaccharides relates to the transcellular route of calcium absorption in the large intestine of rats.
The Journal of Nutrition Vol. 128 No. 6 June 1998,
pp. 934-939
Copyright ©1998 by the American Society for Nutritional Sciences
This article has been cited by other articles:
|
|
 |
|
  K. E. Scholz-Ahrens and J. Schrezenmeir Inulin and Oligofructose and Mineral Metabolism: The Evidence from Animal Trials J. Nutr., November 1, 2007; 137(11): 2513S - 2523S. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Coxam Current Data with Inulin-Type Fructans and Calcium, Targeting Bone Health in Adults J. Nutr., November 1, 2007; 137(11): 2527S - 2533S. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Yasuda, K. R. Roneker, D. D. Miller, R. M. Welch, and X. G. Lei Supplemental Dietary Inulin Affects the Bioavailability of Iron in Corn and Soybean Meal to Young Pigs J. Nutr., December 1, 2006; 136(12): 3033 - 3038. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Lopez-Huertas, B. Teucher, J. J Boza, A. Martinez-Ferez, G. Majsak-Newman, L. Baro, J. J Carrero, M. Gonzalez-Santiago, J. Fonolla, and S. Fairweather-Tait Absorption of calcium from milks enriched with fructo-oligosaccharides, caseinophosphopeptides, tricalcium phosphate, and milk solids Am. J. Clinical Nutrition, February 1, 2006; 83(2): 310 - 316. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. A. Zafar, C. M. Weaver, Y. Zhao, B. R. Martin, and M. E. Wastney Nondigestible Oligosaccharides Increase Calcium Absorption and Suppress Bone Resorption in Ovariectomized Rats J. Nutr., February 1, 2004; 134(2): 399 - 402. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. C. Kruger, K. E. Brown, G. Collett, L. Layton, and L. M. Schollum The Effect of Fructooligosaccharides with Various Degrees of Polymerization on Calcium Bioavailability in the Growing Rat Experimental Biology and Medicine, June 1, 2003; 228(6): 683 - 688. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Tahiri, J. C Tressol, J. Arnaud, F. R. Bornet, C. Bouteloup-Demange, C. Feillet-Coudray, M. Brandolini, V. Ducros, D. Pepin, F. Brouns, et al. Effect of short-chain fructooligosaccharides on intestinal calcium absorption and calcium status in postmenopausal women: a stable-isotope study Am. J. Clinical Nutrition, February 1, 2003; 77(2): 449 - 457. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. B. Roberfroid, J. Cumps, and J. P. Devogelaer Dietary Chicory Inulin Increases Whole-Body Bone Mineral Density in Growing Male Rats J. Nutr., December 1, 2002; 132(12): 3599 - 3602. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. W. Lopez, M.-A. Levrat-Verny, C. Coudray, C. Besson, V. Krespine, A. Messager, C. Demigné, and C. Rémésy Class 2 Resistant Starches Lower Plasma and Liver Lipids and Improve Mineral Retention in Rats J. Nutr., April 1, 2001; 131(4): 1283 - 1289. [Abstract] [Full Text]
|
|
|
|
|
|
K. E Scholz-Ahrens, G. Schaafsma, E. G. van den Heuvel, and J. Schrezenmeir Effects of prebiotics on mineral metabolism Am. J. Clinical Nutrition, February 1, 2001; 73(2): 459S - 464. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Takahara, T. Morohashi, T. Sano, A. Ohta, S. Yamada, and R. Sasa Fructooligosaccharide Consumption Enhances Femoral Bone Volume and Mineral Concentrations in Rats J. Nutr., July 1, 2000; 130(7): 1792 - 1795. [Abstract] [Full Text]
|
|
|
|
|
|
K. Sakai, A. Ohta, K. Shiga, M. Takasaki, T. Tokunaga, and H. Hara The Cecum and Dietary Short-Chain Fructooligosaccharides Are Involved in Preventing Postgastrectomy Anemia in Rats J. Nutr., June 1, 2000; 130(6): 1608 - 1612. [Abstract] [Full Text]
|
|
