![]() |
|
|
Manuscript received 25 March 1997. Initial reviews completed 2 June 1997. Revision accepted 7 January 1998.
,
* Centro de Química de Proteínas and
Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, 14049-900, S.P., Brazil
Burn patients develop pathophysiological alterations, which include extensive nitrogen loss, malnutrition, markedly increased metabolic rate and immunologic deficiency. This predisposes burn patients to frequent infections, poor wound healing, increased length of hospitalization and increased mortality. The nutritional support requires high protein and high energy diets preferably administered enterally soon after injury. The effects of increased dietary components such as glutamine, arginine and (n-3) fatty acids and related compounds have been evaluated in burn victims. These components, when supplied in quantities two to seven times of those in normal diets of healthy persons, appear to have beneficial pharmacological effects on the pathophysiological alterations associated with burns. However, the efficacy of immune-enhancing diets remains to be convincingly shown.
Key words: burns, pharmacological nutrition, glutamine, arginine, (n-3) fatty acids.
The Journal of Nutrition Vol. 128 No. 5 May 1998,
pp. 797-803
Copyright ©1998 by the American Society for Nutritional Sciences
This article has been cited by other articles:
![]() |
U. Ha and S. Jin Expression of the soxR Gene of Pseudomonas aeruginosa Is Inducible during Infection of Burn Wounds in Mice and Is Required To Cause Efficient Bacteremia Infect. Immun., October 1, 1999; 67(10): 5324 - 5331. [Abstract] [Full Text] [PDF] |
||||