![[Feedback]](/icons/banner/feedbackACT.gif){kind=icon}
![[For Subscribers]](/icons/banner/subscriberACT.gif){kind=icon}
![[Archive]](/icons/banner/archiveACT.gif){kind=icon}
![[Search]](/icons/banner/searchACT.gif){kind=icon}
![[Contents]](/icons/banner/tocACT.gif){kind=icon}
|
|
|
|
|
||
Manuscript received 17 July 1997. Initial reviews completed 5 September 1997. Revision accepted 5 November, 1997.
,
* Nutritional Science Center, Bioscience Laboratories, Meiji Seika Kaisha, Ltd., Saitama 350-02, Japan; Department of Nutrition, Faculty of Agriculture, Tokyo University of Agriculture, Tokyo 156, Japan; and ** Department of Bioscience and Chemistry, Faculty of Agriculture, Hokkaido University, Sapporo 060, Japan
Gastrectomized rats develop anemia and osteopenia, and ingestion of fructooligosaccharides leads to an increase in iron absorption and promotes recovery from anemia in iron-deficient rats. Laparotomized (sham-operated control) rats and totally gastrectomized (Billoth II) rats, in groups of 14 each, were fed a control diet without fructooligosaccharides or a diet containing fructooligosaccharides (75 g/kg of diet) for 6 wk. All rats received an intramuscular injection of vitamin B-12 every 2 wk. Tail blood was collected every week for determination of hematocrit and hemoglobin concentration. At the end of the experiment, the rats were killed and the femur and tibia were collected for measurement of bone mineral density (BMD). The hematocrit, hemoglobin concentration, hemoglobin regeneration efficiency, and BMD of both femurs and tibias were significantly lower in gastrectomized rats fed the control diet than in the other three groups. Dietary fructooligosaccharides prevented anemia and osteopenia in totally gastrectomized rats.
Key words: rats, gastrectomy, fructooligosaccharides, anemia, osteopenia.
The Journal of Nutrition Vol. 128 No. 3 March 1998,
pp. 485-490
Copyright ©1998 by the American Society for Nutritional Sciences
This article has been cited by other articles:
|
|
 |
|
  D. Perez-Conesa, G. Lopez, and G. Ros Effect of Probiotic, Prebiotic and Synbiotic Follow-up Infant Formulas on Iron Bioavailability in Rats Food Science and Technology International, February 1, 2007; 13(1): 69 - 77. [Abstract] [PDF]
|
|
|
|
 |
|
 K. Yasuda, K. R. Roneker, D. D. Miller, R. M. Welch, and X. G. Lei Supplemental Dietary Inulin Affects the Bioavailability of Iron in Corn and Soybean Meal to Young Pigs J. Nutr., December 1, 2006; 136(12): 3033 - 3038. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Afsana, K. Shiga, S. Ishizuka, and H. Hara Ingestion of an Indigestible Saccharide, Difructose Anhydride III, Partially Prevents the Tannic Acid-Induced Suppression of Iron Absorption in Rats J. Nutr., November 1, 2003; 133(11): 3553 - 3560. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Shiga, H. Hara, G. Okano, and Y. Aoyama Ingestion of Water-Soluble Soybean Fiber Prevents Gastrectomy-Induced Iron Malabsorption, Anemia and Impairment of Voluntary Running Exercise Performance in Rats J. Nutr., April 1, 2003; 133(4): 1120 - 1126. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. B. Roberfroid, J. Cumps, and J. P. Devogelaer Dietary Chicory Inulin Increases Whole-Body Bone Mineral Density in Growing Male Rats J. Nutr., December 1, 2002; 132(12): 3599 - 3602. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. P. Pescarmona, P. D'Amelio, E. Morra, and G. C. Isaia Haptoglobin genotype as a risk factor for postmenopausal osteoporosis J. Med. Genet., September 1, 2001; 38(9): 636 - 638. [Full Text] [PDF]
|
|
|
|
 |
|
 D. L. Topping and P. M. Clifton Short-Chain Fatty Acids and Human Colonic Function: Roles of Resistant Starch and Nonstarch Polysaccharides Physiol Rev, July 1, 2001; 81(3): 1031 - 1064. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. E Scholz-Ahrens, G. Schaafsma, E. G. van den Heuvel, and J. Schrezenmeir Effects of prebiotics on mineral metabolism Am. J. Clinical Nutrition, February 1, 2001; 73(2): 459S - 464. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Takahara, T. Morohashi, T. Sano, A. Ohta, S. Yamada, and R. Sasa Fructooligosaccharide Consumption Enhances Femoral Bone Volume and Mineral Concentrations in Rats J. Nutr., July 1, 2000; 130(7): 1792 - 1795. [Abstract] [Full Text]
|
|
|
|
|
|
K. Sakai, A. Ohta, K. Shiga, M. Takasaki, T. Tokunaga, and H. Hara The Cecum and Dietary Short-Chain Fructooligosaccharides Are Involved in Preventing Postgastrectomy Anemia in Rats J. Nutr., June 1, 2000; 130(6): 1608 - 1612. [Abstract] [Full Text]
|
|
