Journal of Nutrition OpenSOurce Diets- www.ResearchDiets.com

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
 QUICK SEARCH:   [advanced]


     


This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Roberfroid, M. B.
Right arrow Articles by Gibson, G. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Roberfroid, M. B.
Right arrow Articles by Gibson, G. R.

The Bifidogenic Nature of Chicory Inulin and Its Hydrolysis Products

Manuscript received 20 February 1997. Initial reviews completed 25 April 1997. Revision accepted 2 September 1997.

Marcel B. Roberfroid*, , Jan A. E. Van Loodagger , and Glenn R. Gibson**

* Unité de Biochimie Toxicologique et Cancérologique, Department of Pharmaceutical Sciences, Université Catholique de Louvain, B1200 Brussels, Belgium; dagger  ORAFTI, B3300 Tienen, Belgium; and ** Microbiology Department, Institute of Food Research, Reading Laboratory, Earley Gate, Reading, U.K.

Research data on the bifidogenic effect of beta (2-1)fructans, which at present are commercialized in the U.S., Japan and Europe as food ingredients, are presented. These food ingredients originate from two different sources. Short-chain fructo-oligosaccharides are synthesized from sucrose and are composed of GFn [n beta (2-1) linked fructose moieties bound to a glucose molecule; 2 <=  n <= 4]. The longer chain length molecule inulin is extracted with hot water from chicory roots (Cichorium intybus) and is also composed of GFn molecules (with 2 < n < 60). Oligofructose is a partial hydrolysate of inulin and is composed of GFn and Fm molecules (n and m indicate the number of fructose moieties with 2 <=  n, <=  7). All types of beta (2-1)fructans are well fermented by intestinal bacteria. For a given chain length, there is no difference in fermentation rate between GFn- and Fm-type beta -fructans. In vitro fermentation of inulin revealed that molecules with a chain length (degree of polymerization or DP) > 10 are fermented on average half as quickly as molecules with a DP < 10. All beta (2-1)fructans are bifidogenic and classified as biobiotics.

Key words: inulin, oligofructose, bifidobacteria, bifidogenicity, dose effect, prebiotic.

The Journal of Nutrition Vol. 128 No. 1 January 1998, pp. 11-19
Copyright ©1998 by the American Society for Nutritional Sciences




This article has been cited by other articles:


Home page
J. Nutr.Home page
M. B. Roberfroid
Inulin-Type Fructans: Functional Food Ingredients
J. Nutr., November 1, 2007; 137(11): 2493S - 2502S.
[Abstract] [Full Text] [PDF]


Home page
J. Nutr.Home page
C. H. M. Leenen and L. A. Dieleman
Inulin and Oligofructose in Chronic Inflammatory Bowel Disease
J. Nutr., November 1, 2007; 137(11): 2572S - 2575S.
[Abstract] [Full Text] [PDF]


Home page
J. Nutr.Home page
K. M. Tuohy
Inulin-Type Fructans in Healthy Aging
J. Nutr., November 1, 2007; 137(11): 2590S - 2593S.
[Abstract] [Full Text] [PDF]


Home page
J. Nutr.Home page
M. Roberfroid
Prebiotics: The Concept Revisited
J. Nutr., March 1, 2007; 137(3): 830S - 837S.
[Abstract] [Full Text] [PDF]


Home page
Appl. Environ. Microbiol.Home page
G. Falony, A. Vlachou, K. Verbrugghe, and L. D. Vuyst
Cross-Feeding between Bifidobacterium longum BB536 and Acetate-Converting, Butyrate-Producing Colon Bacteria during Growth on Oligofructose
Appl. Envir. Microbiol., December 1, 2006; 72(12): 7835 - 7841.
[Abstract] [Full Text] [PDF]


Home page
Appl. Environ. Microbiol.Home page
T. Vanhoutte, V. De Preter, E. De Brandt, K. Verbeke, J. Swings, and G. Huys
Molecular Monitoring of the Fecal Microbiota of Healthy Human Subjects during Administration of Lactulose and Saccharomyces boulardii
Appl. Envir. Microbiol., September 1, 2006; 72(9): 5990 - 5997.
[Abstract] [Full Text] [PDF]


Home page
Appl. Environ. Microbiol.Home page
Y. Nakanishi, K. Murashima, H. Ohara, T. Suzuki, H. Hayashi, M. Sakamoto, T. Fukasawa, H. Kubota, A. Hosono, T. Kono, et al.
Increase in Terminal Restriction Fragments of Bacteroidetes-Derived 16S rRNA Genes after Administration of Short-Chain Fructooligosaccharides
Appl. Envir. Microbiol., September 1, 2006; 72(9): 6271 - 6276.
[Abstract] [Full Text] [PDF]


Home page
J DAIRY SCIHome page
M. T. Liong and N. P. Shah
Effects of a Lactobacillus casei Synbiotic on Serum Lipoprotein, Intestinal Microflora, and Organic Acids in Rats
J Dairy Sci, May 1, 2006; 89(5): 1390 - 1399.
[Abstract] [Full Text] [PDF]


Home page
J Exp BotHome page
W. Van den Ende, S. Clerens, R. Vergauwen, D. Boogaerts, K. Le Roy, L. Arckens, and A. Van Laere
Cloning and functional analysis of a high DP fructan:fructan 1-fructosyl transferase from Echinops ritro (Asteraceae): comparison of the native and recombinant enzymes
J. Exp. Bot., March 1, 2006; 57(4): 775 - 789.
[Abstract] [Full Text] [PDF]


Home page
Appl. Environ. Microbiol.Home page
S. Mueller, K. Saunier, C. Hanisch, E. Norin, L. Alm, T. Midtvedt, A. Cresci, S. Silvi, C. Orpianesi, M. C. Verdenelli, et al.
Differences in Fecal Microbiota in Different European Study Populations in Relation to Age, Gender, and Country: a Cross-Sectional Study
Appl. Envir. Microbiol., February 1, 2006; 72(2): 1027 - 1033.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
E. Lopez-Huertas, B. Teucher, J. J Boza, A. Martinez-Ferez, G. Majsak-Newman, L. Baro, J. J Carrero, M. Gonzalez-Santiago, J. Fonolla, and S. Fairweather-Tait
Absorption of calcium from milks enriched with fructo-oligosaccharides, caseinophosphopeptides, tricalcium phosphate, and milk solids
Am. J. Clinical Nutrition, February 1, 2006; 83(2): 310 - 316.
[Abstract] [Full Text] [PDF]


Home page
J. Nutr.Home page
C. L. Kien, M. Schmitz-Brown, T. Solley, D. Sun, and W. L. Frankel
Increased Colonic Luminal Synthesis of Butyric Acid Is Associated with Lowered Colonic Cell Proliferation in Piglets
J. Nutr., January 1, 2006; 136(1): 64 - 69.
[Abstract] [Full Text] [PDF]


Home page
Appl. Environ. Microbiol.Home page
L. Makras, G. Van Acker, and L. De Vuyst
Lactobacillus paracasei subsp. paracasei 8700:2 Degrades Inulin-Type Fructans Exhibiting Different Degrees of Polymerization
Appl. Envir. Microbiol., November 1, 2005; 71(11): 6531 - 6537.
[Abstract] [Full Text] [PDF]


Home page
J. Nutr.Home page
G. Tzortzis, A. K. Goulas, J. M. Gee, and G. R. Gibson
A Novel Galactooligosaccharide Mixture Increases the Bifidobacterial Population Numbers in a Continuous In Vitro Fermentation System and in the Proximal Colonic Contents of Pigs In Vivo
J. Nutr., July 1, 2005; 135(7): 1726 - 1731.
[Abstract] [Full Text] [PDF]


Home page
J. Nutr.Home page
R. A. Rastall
Bacteria in the Gut: Friends and Foes and How to Alter the Balance
J. Nutr., August 1, 2004; 134(8): 2022S - 2026S.
[Abstract] [Full Text] [PDF]


Home page
J Exp BotHome page
A. Michiels, A. Van Laere, W. Van den Ende, and M. Tucker
Expression analysis of a chicory fructan 1-exohydrolase gene reveals complex regulation by cold
J. Exp. Bot., June 1, 2004; 55(401): 1325 - 1333.
[Abstract] [Full Text] [PDF]


Home page
Appl. Environ. Microbiol.Home page
R. Van der Meulen, L. Avonts, and L. De Vuyst
Short Fractions of Oligofructose Are Preferentially Metabolized by Bifidobacterium animalis DN-173 010
Appl. Envir. Microbiol., April 1, 2004; 70(4): 1923 - 1930.
[Abstract] [Full Text] [PDF]


Home page
GutHome page
S J M Ten Bruggencate, I M J Bovee-Oudenhoven, M L G Lettink-Wissink, M B Katan, and R Van der Meer
Dietary fructo-oligosaccharides and inulin decrease resistance of rats to salmonella: protective role of calcium
Gut, April 1, 2004; 53(4): 530 - 535.
[Abstract] [Full Text] [PDF]


Home page
Plant Physiol.Home page
W. Van den Ende, S. Clerens, R. Vergauwen, L. Van Riet, A. Van Laere, M. Yoshida, and A. Kawakami
Fructan 1-Exohydrolases. beta -(2,1)-Trimmers during Graminan Biosynthesis in Stems of Wheat? Purification, Characterization, Mass Mapping, and Cloning of Two Fructan 1-Exohydrolase Isoforms
Plant Physiology, February 1, 2003; 131(2): 621 - 631.
[Abstract] [Full Text] [PDF]


Home page
CarcinogenesisHome page
A. P. Femia, C. Luceri, P. Dolara, A. Giannini, A. Biggeri, M. Salvadori, Y. Clune, K. J. Collins, M. Paglierani, and G. Caderni
Antitumorigenic activity of the prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis on azoxymethane-induced colon carcinogenesis in rats
Carcinogenesis, November 1, 2002; 23(11): 1953 - 1960.
[Abstract] [Full Text] [PDF]


Home page
J. Nutr.Home page
M. Verghese, D. R. Rao, C. B. Chawan, and L. Shackelford
Dietary Inulin Suppresses Azoxymethane-Induced Preneoplastic Aberrant Crypt Foci in Mature Fisher 344 Rats
J. Nutr., September 1, 2002; 132(9): 2804 - 2808.
[Abstract] [Full Text] [PDF]


Home page
Arch. Dis. Child. Fetal Neonatal Ed.Home page
G Boehm, M Lidestri, P Casetta, J Jelinek, F Negretti, B Stahl, and A Marini
Supplementation of a bovine milk formula with an oligosaccharide mixture increases counts of faecal bifidobacteria in preterm infants
Arch. Dis. Child. Fetal Neonatal Ed., May 1, 2002; 86(3): F178 - F181.
[Abstract] [Full Text] [PDF]


Home page
J. Nutr.Home page
K. K. Buddington, J. B. Donahoo, and R. K. Buddington
Dietary Oligofructose and Inulin Protect Mice from Enteric and Systemic Pathogens and Tumor Inducers
J. Nutr., March 1, 2002; 132(3): 472 - 477.
[Abstract] [Full Text] [PDF]


Home page
J Med MicrobiolHome page
A.J. McBAIN and G.T. MACFARLANE
Modulation of genotoxic enzyme activities by non-digestible oligosaccharide metabolism in in-vitro human gut bacterial ecosystems
J. Med. Microbiol., September 1, 2001; 50(9): 833 - 842.
[Abstract] [Full Text] [PDF]


Home page
Plant Physiol.Home page
W. Van den Ende, A. Michiels, D. Van Wonterghem, S. P. Clerens, J. De Roover, and A. J. Van Laere
Defoliation Induces Fructan 1-Exohydrolase II in Witloof Chicory Roots. Cloning and Purification of Two Isoforms, Fructan 1-Exohydrolase IIa and Fructan 1-Exohydrolase IIb. Mass Fingerprint of the Fructan 1-Exohydrolase II Enzymes
Plant Physiology, July 1, 2001; 126(3): 1186 - 1195.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
M. B Roberfroid
Prebiotics: preferential substrates for specific germs?
Am. J. Clinical Nutrition, February 1, 2001; 73(2): 406S - 409.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
K. E Scholz-Ahrens, G. Schaafsma, E. G. van den Heuvel, and J. Schrezenmeir
Effects of prebiotics on mineral metabolism
Am. J. Clinical Nutrition, February 1, 2001; 73(2): 459S - 464.
[Abstract] [Full Text] [PDF]


Home page
CarcinogenesisHome page
R. Hughes and I.R. Rowland
Stimulation of apoptosis by two prebiotic chicory fructans in the rat colon
Carcinogenesis, January 1, 2001; 22(1): 43 - 47.
[Abstract] [Full Text] [PDF]


Home page
Appl. Environ. Microbiol.Home page
H. Kaplan and R. W. Hutkins
Fermentation of Fructooligosaccharides by Lactic Acid Bacteria and Bifidobacteria
Appl. Envir. Microbiol., June 1, 2000; 66(6): 2682 - 2684.
[Abstract] [Full Text]


Home page
Am. J. Clin. Nutr.Home page
M. B Roberfroid
Prebiotics and probiotics: are they functional foods?
Am. J. Clinical Nutrition, June 1, 2000; 71(6): 1682S - 1687.
[Abstract] [Full Text] [PDF]


Home page
J. Nutr.Home page
E. Menne and N. Guggenbuhl
Fn-type Chicory Inulin Hydrolysate Has a Prebiotic Effect in Humans
J. Nutr., May 1, 2000; 130(5): 1197 - 1199.
[Abstract] [Full Text]


Home page
J. Nutr.Home page
M. B. Roberfroid
Concepts in Functional Foods: The Case of Inulin and Oligofructose
J. Nutr., July 1, 1999; 129(7): 1398 - 1398.
[Abstract] [Full Text]


Home page
J. Nutr.Home page
K. R. Niness
Inulin and Oligofructose: What Are They?
J. Nutr., July 1, 1999; 129(7): 1402 - 1402.
[Abstract] [Full Text]


Home page
J. Nutr.Home page
M. B. Roberfroid
Caloric Value of Inulin and Oligofructose
J. Nutr., July 1, 1999; 129(7): 1436 - 1436.
[Abstract] [Full Text]


Home page
J. Nutr.Home page
J. O. Hunter, Q. Tuffnell, and A. J. Lee
Controlled Trial of Oligofructose in the Management of Irritable Bowel Syndrome
J. Nutr., July 1, 1999; 129(7): 1451 - 1451.
[Abstract] [Full Text]




Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]