QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Miller, T. L. Search for Related Content PubMed PubMed Citation Articles by Miller, T. L.

Malnutrition: Metabolic Changes in Children, Comparisons with Adults¹

Harvard Medical School, Combined Program in Pediatric Gastroenterology and Nutrition, Children's Hospital, Boston MA 02115

Nutritional problems of human immunodeficiency virus (HIV)-infected children are common, pervasive, and often frustrating to treat. Because of the strong link between immunity and nutrition, that will be outlined here, clinicians caring for HIV-infected children need to attend to nutritional deficits by trying to help children achieve normal growth. Scientific studies are emerging on the importance of nutrition in both predicting and improving clinical outcomes, such as hospitalization rates and survival. Current background information on pediatric HIV infection and the associations between nutrition and HIV will be provided in this presentation. As well, the growth patterns of HIV-infected children, pathogenesis of nutritional disorders, and current diagnostic and therapeutic interventions will be presented. It is hoped that this presentation will provide both practical advice to clinicians caring for HIV-infected children, as well as serving as a basis to stimulate much needed scientific research in this area.

KEY WORDS: • HIV infection • growth • body composition • wasting • metabolism

¹ Presented at the workshop entitled "Nutrition in Pediatric HIV Infection: Setting the Research Agenda" held in Bethesda, MD on September 28–29, 1995. The workshop was sponsored by the Office of AIDS Research of the National Institutes of Health, the National Institute of Child Health and Human Development, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Allergy and Infectious Diseases, National Institute of Mental Health, Food and Drug Administration, Pediatric AIDS Foundation, National Dairy Council, Sandoz Nutrition Corporation, Bristol-Meyers Squibb Company, Clintec Nutrition Company, Ross Products Division-Abbott Laboratories, Serono Laboratories, Inc., and the American Institute of Nutrition. Workshop proceedings are published as a supplement to The Journal of Nutrition. Guest Editors for this supplement publication were Daniel J. Raiten and John M. Talbot, Life Sciences Research Office, Federation of American Societies for Experimental Biology, Bethesda, MD.