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MRC Dunn Clinical Nutrition Centre, Cambridge, United Kingdom * Unité de Biochimie Toxicologique et Cancérologique, Départment des Sciences Pharmaceutiques, Université Catholique de Louvain, Brussels, Belgium
Because the human gut microbiota can play a major role in host health, there is currently some interest in the manipulation of the composition of the gut flora towards a potentially more remedial community. Attempts have been made to increase bacterial groups such as Bifidobacterium and Lactobacillus that are perceived as exerting health-promoting properties. Probiotics, defined as microbial food supplements that beneficially affect the host by improving its intestinal microbial balance, have been used to change the composition of colonic microbiota. However, such changes may be transient, and the implantation of exogenous bacteria therefore becomes limited. In contrast, prebiotics are nondigestible food ingredients that beneficially affect the host by selectively stimulating the growth and/or activity of one or a limited number of bacterial species already resident in the colon, and thus attempt to improve host health. Intake of prebiotics can significantly modulate the colonic microbiota by increasing the number of specific bacteria and thus changing the composition of the microbiota. Nondigestible oligosaccharides in general, and fructooligosaccharides in particular, are prebiotics. They have been shown to stimulate the growth of endogenous bifidobacteria, which, after a short feeding period, become predominant in human feces. Moreover, these prebiotics modulate lipid metabolism, most likely via fermentation products. By combining the rationale of pro- and prebiotics, the concept of synbiotics is proposed to characterize some colonic foods with interesting nutritional properties that make these compounds candidates for classification as health-enhancing functional food ingredients.
KEY WORDS: • colon • humans • microbiota • prebiotics • probiotics
1 To whom correspondence should be addressed.
Manuscript received 8 July 1994. Revision accepted 20 December 1994.
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|
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|
|
|
|
|
|
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|
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|
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|
|
|
|
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|
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|
|
|
|
|
|
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|
|
|
|
|
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|
|
|
|
|
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|
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|
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|
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|
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|
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|
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|
|
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|
|
|
|
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|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
S. Kolida and G. R. Gibson Prebiotic Capacity of Inulin-Type Fructans J. Nutr., November 1, 2007; 137(11): 2503S - 2506S. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
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|
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|
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|
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|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
M. Roberfroid Prebiotics: The Concept Revisited J. Nutr., March 1, 2007; 137(3): 830S - 837S. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
T. Vanhoutte, V. De Preter, E. De Brandt, K. Verbeke, J. Swings, and G. Huys Molecular Monitoring of the Fecal Microbiota of Healthy Human Subjects during Administration of Lactulose and Saccharomyces boulardii Appl. Envir. Microbiol., September 1, 2006; 72(9): 5990 - 5997. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Nakanishi, K. Murashima, H. Ohara, T. Suzuki, H. Hayashi, M. Sakamoto, T. Fukasawa, H. Kubota, A. Hosono, T. Kono, et al. Increase in Terminal Restriction Fragments of Bacteroidetes-Derived 16S rRNA Genes after Administration of Short-Chain Fructooligosaccharides Appl. Envir. Microbiol., September 1, 2006; 72(9): 6271 - 6276. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. D. Cabana, A. L. Shane, C. Chao, and M. Oliva-Hemker Probiotics in Primary Care Pediatrics Clinical Pediatrics, June 1, 2006; 45(5): 405 - 410. [Abstract] [PDF]
|
|
|
|
|
|
A. Belenguer, S. H. Duncan, A. G. Calder, G. Holtrop, P. Louis, G. E. Lobley, and H. J. Flint Two Routes of Metabolic Cross-Feeding between Bifidobacterium adolescentis and Butyrate-Producing Anaerobes from the Human Gut. Appl. Envir. Microbiol., May 1, 2006; 72(5): 3593 - 3599. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. A. Ferens, R. Cobbold, and C. J. Hovde Intestinal Shiga Toxin-Producing Escherichia coli Bacteria Mitigate Bovine Leukemia Virus Infection in Experimentally Infected Sheep. Infect. Immun., May 1, 2006; 74(5): 2906 - 2916. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. K. Keel and J. G. Songer The Comparative Pathology of Clostridium difficile-associated Disease Vet. Pathol., May 1, 2006; 43(3): 225 - 240. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. T. Liong and N. P. Shah Effects of a Lactobacillus casei Synbiotic on Serum Lipoprotein, Intestinal Microflora, and Organic Acids in Rats J Dairy Sci, May 1, 2006; 89(5): 1390 - 1399. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Loh, M. Eberhard, R. M. Brunner, U. Hennig, S. Kuhla, B. Kleessen, and C. C. Metges Inulin Alters the Intestinal Microbiota and Short-Chain Fatty Acid Concentrations in Growing Pigs Regardless of Their Basal Diet J. Nutr., May 1, 2006; 136(5): 1198 - 1202. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Haarman and J. Knol Quantitative Real-Time PCR Analysis of Fecal Lactobacillus Species in Infants Receiving a Prebiotic Infant Formula Appl. Envir. Microbiol., April 1, 2006; 72(4): 2359 - 2365. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Barrangou, M. A. Azcarate-Peril, T. Duong, S. B. Conners, R. M. Kelly, and T. R. Klaenhammer Global analysis of carbohydrate utilization by Lactobacillus acidophilus using cDNA microarrays PNAS, March 7, 2006; 103(10): 3816 - 3821. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Snart, R. Bibiloni, T. Grayson, C. Lay, H. Zhang, G. E. Allison, J. K. Laverdiere, F. Temelli, T. Vasanthan, R. Bell, et al. Supplementation of the diet with high-viscosity Beta-glucan results in enrichment for lactobacilli in the rat cecum. Appl. Envir. Microbiol., March 1, 2006; 72(3): 1925 - 1931. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Crittenden, R. Weerakkody, L. Sanguansri, and M. Augustin Synbiotic Microcapsules That Enhance Microbial Viability during Nonrefrigerated Storage and Gastrointestinal Transit. Appl. Envir. Microbiol., March 1, 2006; 72(3): 2280 - 2282. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Van der Meulen, L. Makras, K. Verbrugghe, T. Adriany, and L. De Vuyst In Vitro Kinetic Analysis of Oligofructose Consumption by Bacteroides and Bifidobacterium spp. Indicates Different Degradation Mechanisms Appl. Envir. Microbiol., February 1, 2006; 72(2): 1006 - 1012. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Dinoto, A. Suksomcheep, S. Ishizuka, H. Kimura, S. Hanada, Y. Kamagata, K. Asano, F. Tomita, and A. Yokota Modulation of Rat Cecal Microbiota by Administration of Raffinose and Encapsulated Bifidobacterium breve Appl. Envir. Microbiol., January 1, 2006; 72(1): 784 - 792. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. L. Kien, M. Schmitz-Brown, T. Solley, D. Sun, and W. L. Frankel Increased Colonic Luminal Synthesis of Butyric Acid Is Associated with Lowered Colonic Cell Proliferation in Piglets J. Nutr., January 1, 2006; 136(1): 64 - 69. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. J. M. Ten Bruggencate, I. M. J. Bovee-Oudenhoven, M. L. G. Lettink-Wissink, M. B. Katan, and R. van der Meer Dietary Fructooligosaccharides Affect Intestinal Barrier Function in Healthy Men J. Nutr., January 1, 2006; 136(1): 70 - 74. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Clavel, M. Fallani, P. Lepage, F. Levenez, J. Mathey, V. Rochet, M. Serezat, M. Sutren, G. Henderson, C. Bennetau-Pelissero, et al. Isoflavones and Functional Foods Alter the Dominant Intestinal Microbiota in Postmenopausal Women J. Nutr., December 1, 2005; 135(12): 2786 - 2792. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Altermann, W. M. Russell, M. A. Azcarate-Peril, R. Barrangou, B. L. Buck, O. McAuliffe, N. Souther, A. Dobson, T. Duong, M. Callanan, et al. Inaugural Article: From the Cover: Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM PNAS, March 15, 2005; 102(11): 3906 - 3912. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Bouhnik, L. Raskine, G. Simoneau, E. Vicaut, C. Neut, B. Flourie, F. Brouns, and F. R Bornet The capacity of nondigestible carbohydrates to stimulate fecal bifidobacteria in healthy humans: a double-blind, randomized, placebo-controlled, parallel-group, dose-response relation study Am. J. Clinical Nutrition, December 1, 2004; 80(6): 1658 - 1664. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. L. Diaz, L. Hoang, J. Wang, J. L. Vela, S. Jenkins, R. Aranda, and M. G. Martin Maternal Adaptive Immunity Influences the Intestinal Microflora of Suckling Mice J. Nutr., September 1, 2004; 134(9): 2359 - 2364. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. A. Lawson, Y. Song, C. Liu, D. R. Molitoris, M.-L. Vaisanen, M. D. Collins, and S. M. Finegold Anaerotruncus colihominis gen. nov., sp. nov., from human faeces Int J Syst Evol Microbiol, March 1, 2004; 54(2): 413 - 417. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. R. Zabarovsky, L. Petrenko, A. Protopopov, O. Vorontsova, A. S. Kutsenko, Y. Zhao, G. Kilosanidze, V. Zabarovska, E. Rakhmanaliev, B. Pettersson, et al. Restriction site tagged (RST) microarrays: a novel technique to study the species composition of complex microbial systems Nucleic Acids Res., August 15, 2003; 31(16): e95 - e95. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. K. Le Leu, I. L. Brown, Y. Hu, and G. P. Young Effect of resistant starch on genotoxin-induced apoptosis, colonic epithelium, and lumenal contents in rats Carcinogenesis, August 1, 2003; 24(8): 1347 - 1352. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Barrangou, E. Altermann, R. Hutkins, R. Cano, and T. R. Klaenhammer Functional and comparative genomic analyses of an operon involved in fructooligosaccharide utilization by Lactobacillus acidophilus PNAS, July 22, 2003; 100(15): 8957 - 8962. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Zabarovska, A. S. Kutsenko, L. Petrenko, G. Kilosanidze, O. Ljungqvist, E. Norin, T. Midtvedt, G. Winberg, R. Mollby, V. I. Kashuba, et al. NotI passporting to identify species composition of complex microbial systems Nucleic Acids Res., January 15, 2003; 31(2): e5 - e5. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Nangia-Makker, V. Hogan, Y. Honjo, S. Baccarini, L. Tait, R. Bresalier, and A. Raz Inhibition of Human Cancer Cell Growth and Metastasis in Nude Mice by Oral Intake of Modified Citrus Pectin J Natl Cancer Inst, December 18, 2002; 94(24): 1854 - 1862. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R.J. Kennedy, S.J. Kirk, and K.R. Gardiner Promotion of a Favorable Gut Flora in Inflammatory Bowel Disease JPEN J Parenter Enteral Nutr, May 1, 2000; 24(3): 189 - 195. [Abstract] [PDF]
|
|
|
|
|
|
P. Ruperez Oligosacaridos bifidogenicos: Bifidogenic oligosaccharides Food Science and Technology International, January 1, 1998; 4(4): 237 - 243. [Abstract] [PDF]
|
|
