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Lean and Heavy Women May Not Use Energy from Alcohol with Equal Efficiency1,2,

Beverly A. Clevidence*,3, Philip R. Taylor{dagger}, William S. Campbell{dagger} and Joseph T. Judd*

* Diet and Human Performance Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, U.S. Department of Agriculture, Beltsville, MD 20705-2350 {dagger} Cancer Prevention Studies Branch, Division of Cancer Prevention and Control, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892

To assess whether energy from alcohol is efficiently utilized to maintain body mass, we examined changes in energy intake of young women when they drank alcohol. The women ate controlled diets typical of the American diet with regard to macronutrients. Body weights were controlled to within 1 kg of entry level weights. The subjects were given alcohol (30 g/d) and no alcohol treatments for 3 mo each in a crossover design. The treatments were isoenergetic; for the no alcohol treatment alcohol energy was replaced with energy from carbohydrate. The average change in energy intake associated with the alcohol treatment was negligible when all subjects were considered collectively. There was, however, a divergence in response between lean and heavy subjects. Fifteen women required, on average, an additional 886 ± 147 (mean ± SEM) kJ/d to maintain body weight during the alcohol treatment, and these women were leaner (body mass index 22.6 ± 0.8 kg/m2 vs. 25.2 ± 1.0, P < 0.05) than the 22 women who required, on average, 559 ± 139 fewer kJ/d when on the alcohol treatment. This study suggests that all subjects do not use energy from alcohol with equal efficiency.


KEY WORDS: • alcohol • energy • body mass index • humans

1 Supported in part by funds from a National Cancer Institute/U.S. Department of Agriculture Interagency Agreement (Y01-CN-40620).

2 The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked "advertisement" in accordance with 18 USC section 1734 solely to indicate this fact.

3 To whom correspondence should be addressed: Diet and Human Performance Laboratory, Bldg 308 Rm 116, BARC-East, 10300 Baltimore Avenue, Beltsville, MD 20705-2350.

Manuscript received 21 November 1994. Revision accepted 17 May 1995.







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