![[Feedback]](/icons/banner/feedbackACT.gif){kind=icon}
![[For Subscribers]](/icons/banner/subscriberACT.gif){kind=icon}
![[Archive]](/icons/banner/archiveACT.gif){kind=icon}
![[Search]](/icons/banner/searchACT.gif){kind=icon}
![[Contents]](/icons/banner/tocACT.gif){kind=icon}
|
|
|
|
|
||
Department of Medicine II and Clinical Nutrition, University of Göteborg, Sahlgrenska Hospital * Department of Food Science, Chalmers University of Technology, S-413 45 Göteborg, Sweden
Iron absorption was measured from five kinds of bread made from various types of flour and fermented in different ways in order to obtain a wide variation in the content of fiber, phytate (inositol hexaphosphate) and its degradation products, inorganic phosphate and inositol phosphates with fewer numbers of phosphate groups (inositol pentaphosphate through monophosphate). Each experiment had 9–10 subjects and, in each subject, iron absorption was measured from control rolls made from low extraction wheat flour and one kind of test roll using two different radioiron tracers: 55Fe and 59Fe. The inhibition of iron absorption was closely related to the content of phytate-phosphorous as determined using the AOAC method, and to the sum of the tri- through hexaphosphate groups as determined using the HPLC method. As an example, prolonged fermentation of whole-rye bread reduced total inositol phosphates to the same amount as in the control rolls and increased fractional iron absorption to the same high level, in spite of a fiber content five times as great. The results strongly suggest that the inhibitory effect of bran on iron absorption is due to its content of phytate and other inositol phosphates present after fermentation, rather than to its content of fiber or other constituents. Thus, effective fermentation will increase the bioavailability of iron in whole-meal bread.
KEY WORDS: • iron absorption • phytate • inositol phosphates • fiber • humans
1 Supported by grants from the Swedish Medical Research Council Project, B88 - 19X-04721-13B, the Swedish Council for Forestry and Agriculture Research, 864/86, 31:2 and 599-89L-135:2 and the Swedish Agency for Research Co-operation with Developing Countries 9.49/SAREC 85/46:2.
2 To whom correspondence and reprint requests should be addressed.
Manuscript received 19 November 1990. Revision accepted 22 August 1991.
This article has been cited by other articles:
|
|
 |
|
  H. Inoue, T. Kobayashi, T. Nozoye, M. Takahashi, Y. Kakei, K. Suzuki, M. Nakazono, H. Nakanishi, S. Mori, and N. K. Nishizawa Rice OsYSL15 Is an Iron-regulated Iron(III)-Deoxymugineic Acid Transporter Expressed in the Roots and Is Essential for Iron Uptake in Early Growth of the Seedlings J. Biol. Chem., February 6, 2009; 284(6): 3470 - 3479. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Pizarro, M. Olivares, E. Hertrampf, S. Nunez, M. Tapia, H. Cori, and D. L. de Romana Ascorbyl palmitate enhances iron bioavailability in iron-fortified bread. Am. J. Clinical Nutrition, October 1, 2006; 84(4): 830 - 834. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. E. Conway, C. A. Geissler, R. C. Hider, R. P. H. Thompson, and J. J. Powell Serum Iron Curves Can Be Used to Estimate Dietary Iron Bioavailability in Humans J. Nutr., July 1, 2006; 136(7): 1910 - 1914. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Hernandez, V. Sousa, S. Villalpando, A. Moreno, I. Montalvo, and M. Lopez-Alarcon Cooking and fe fortification have different effects on fe bioavailability of bread and tortillas. J. Am. Coll. Nutr., February 1, 2006; 25(1): 20 - 25. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Martinez, G. Ros, M.J. Periago, G. Lopez, J. Ortuno, and F. Rincon El acido fitico en la alimentacion humana/Phytic acid in human nutrition Food Science and Technology International, January 1, 1996; 2(4): 201 - 209. [PDF]
|
|
