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Journal of Nutrition Vol. 12 No. 4 October 1936, pp. 413-427
Copyright © 1936 by American Society for Nutrition
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Storage of Vitamin C by Normal Adults Following a Period of Low Intake1

One Figure

Patricia H. O'Hara and Hazel M. Hauck

New York State College of Home Economics, Cornell University, Ithaca

In four cases, the amount of vitamin C necessary to restore the tissues to saturation after a month on a diet very low in vitamin C, ranged from 2200 to 2800 mg., when administered in daily doses of 200 mg.

It is suggested that the difference between intake and excretion up to the point of saturation following prolonged deprivation of vitamin C may afford some indication of the maximum vitamin C reserve. On this basis tissue reserves at saturation appear to be of the order of 2500 to 3000 mg.

In these experiments, capillary resistance did not give an adequate indication of the state of nutrition with respect to vitamin C.

1 The manuscript from which these data were taken was submitted by Patricia H. O'Hara in partial fulfillment of the requirements for the degree of master of science, 1936. The authors wish to express their appreciation to Dr. Helen Bull, who made the medical examinations, and to the subjects without whose cooperation the study would have been impossible.

Manuscript received 12 June 1936.


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