QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Indira, M. Articles by Kurup, P. A. Search for Related Content PubMed PubMed Citation Articles by Indira, M. Articles by Kurup, P. A.

Effects of Neutral Detergent Fiber from Blackgram (Phaseolus mungo) in Rats and Rabbits

Department of Biochemistry, University of Kerala, Kariavattom, Trivandrum 695 581, Kerala State, India

The hypocholesterolemic action of neutral detergent fiber (NDF) from blackgram (Phaseolus mungo) in rats may be due to hemicellulose, since removal of hemicellulose resulted in the loss of cholesterol-lowering action. Blackgram NDF showed different binding affinities for different bile acids, with maximum binding observed with chenodeoxycholic acid, and minimum binding with deoxycholic acid. Fecal excretion of inorganic cations (Mn⁺⁺, Mg⁺⁺, Cu⁺⁺, Fe⁺⁺⁺, Zn⁺⁺, Na⁺ and K⁺) was greater in rats fed blackgram NDF than in rats fed a fiber-free diet. Absorption of glucose and cholesterol was lower in rabbits fed blackgram NDF than in rabbits fed a fiber-free diet. In vitro studies revealed significant binding of inorganic cations and bile acids by blackgram NDF. Cholic acid may be adsorbed on the surface of blackgram NDF.

KEY WORDS: • neutral detergent fiber • acid detergent fiber • hypocholesterolemic action • fecal excretion of inorganic cations • glucose absorption • cholesterol • bile acid binding • blackgram • rat • rabbit

Manuscript received 11 April 1988. Revision accepted 25 April 1989.