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Journal of Nutrition Vol. 119 No. 12_Suppl December 1989, pp. 1832-1838
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Mineral Interactions Relevant to Nutrient Requirements1

Boyd L. O'Dell

Department of Biochemistry, University of Missouri, Columbia, MO 65211

The negative interaction of metal ions is one of the major dietary factors that causes low bioavailability of these nutrients. Interactions of nutritional significance include sodium-potassium, calcium-magnesium, manganese-iron, iron-copper, and zinc-copper. These interactions reach potential importance when the first metal of each pair listed above is in excess and the other is at the lower limit of requirement. The trace element interaction of highest practical significance in human nutrition is the negative effect of excess zinc on copper bioavailability.

KEY WORDS: • metal ions • interaction • bioavailability • limiting nutrient • zinc-copper interaction • infant formulas

1 This paper was presented at a symposium, "Upper Limits of Nutrients in Infant Formulas," November 7–8, 1988, in Iowa City, IA.




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