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Antioxidant Action of Carotenoids¹

Division of Chemistry, National Research Council of Canada, Ottawa, Ontario K1A 0R6 Canada

Several modes of antioxidant action of ß-carotene are discussed. In particular, the focus is on the ability of ß-carotene to function as a chain-breaking antioxidant in a lipid environment at physiological O₂ partial pressures. This is the mode considered most likely to operate in mammalian cells.

KEY WORDS: • ß-carotene • antioxidant • peroxyl radicals

¹ Presented as part of the symposium, "Biological Actions of Carotenoids," given at the 72nd annual meeting of the Federation of American Societies for Experimental Biology, Las Vegas, NV, May 2, 1988, and supported by grants from the BASF Corporation, Hoffmann-LaRoche, and the National Dairy Council.

Manuscript received 13 July 1988. Revision accepted 12 September 1988.

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