Journal of Nutrition Animal Diets/Enrichment Products...

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

Journal of Nutrition Vol. 118 No. 9 September 1988, pp. 1143-1148
Copyright © 1988 by American Society for Nutrition
This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Madar, Z.
Right arrow Articles by Norenberg, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Madar, Z.
Right arrow Articles by Norenberg, C.

Effects of Cottonseed Dietary Fiber on Metabolic Parameters in Diabetic Rats and Non-Insulin-Dependent Diabetic Humans1

Zecharia Madar, Michal Nir, Naomi Trostler and Clara Norenberg

Diabetic Unit Netania and Faculty of Agriculture, Department of Biochemistry and Human Nutrition, Hebrew University, Rehovot, Israel

The objective of this study was to evaluate the effect of gland cottonseed dietary fiber (CSDF) containing 86% dietary fiber (mainly cellulose) on serum glucose levels in diabetic rats and in non-insulin-dependent diabetes mellitus (NIDDM) patients. A diet containing 15% CSDF given to streptozotocin-induced diabetic rats for 30 d tended to reduce the postprandial plasma glucose level curve. Alternatively, CSDF significantly increased fecal weight (15 ± 3 vs. 5 ± 2 g; P < 0.01) and shortened transit time (20 ± 2.24 vs. 11.2 ± 0.8 h). CSDF had no effect on body weight and serum lipid levels. Twelve NIDDM subjects were given a meal tolerance test (MTT) with or without CSDF before and after daily supplementation of CSDF (16.5 g) in pita twice a day for a month. Incremental glucose levels were significantly (P < 0.05) lower at 30, 60 and 180 min after the MTT containing CSDF than in subjects consuming a meal without CSDF. The insulin levels also tended to be lower. The NIDDM subjects tolerated the CSDF well. No flatulence or other side effects were exhibited. Plasma lipid levels remained unchanged. We therefore concluded that CSDF may have a potential benefit in the management of NIDDM.

KEY WORDS: • cottonseed dietary fiber • postprandial glucose level • meal tolerance test

1 This study was supported by a grant from the Miloumor cottonseed processing plant, Israel.

Manuscript received 30 November 1987. Revision accepted 18 April 1988.






Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]