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Protein Deficiency Alters Rat Pancreatic Lipid Composition1

Jeremy S. Wilson, Mark A. Korsten and Charles S. Lieber

Alcohol Research Center, Veterans Administration Medical Center, Bronx, NY and Mount Sinai School of Medicine (CUNY), New York, NY

Pancreatic lipid composition was found to be altered in rats fed a protein-deficient diet for 4 wk. Increases in triglycerides and cholesteryl ester content were found in association with a decrease in phospholipids. Alterations in these lipids may adversely affect membrane function and predispose to pancreatic injury.

KEY WORDS: • protein deficiency • cholesteryl ester • rat pancreas • lipids

1 This study was supported by the Veterans Administration and Department of Health and Human Services Grant AA-03508.

Manuscript received 28 October 1985. Revision accepted 25 April 1986.






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Copyright © 1986 by American Society for Nutrition