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The Effect of Dietary Protein Levels on Diet-Induced Thermogenesis in the Rat¹

Department of Nutritional Sciences, University of Wisconsin-Madison Madison, WI 53706

Relative to rats fed a 15% protein-diet, 300-g rats fed a 5% protein-diet for 5 weeks consumed 19% more food but gained only 28% as much weight, showed twice the thermic response when fed, had twice as much subscapular brown adipose tissue with almost twice the specific GDP-binding activity. There was no difference between these groups in skeletal growth nor, unexpectedly, in the proportion of carcass fat.

KEY WORDS: • thermogenesis • brown adipose tissue • GDP-binding activity • protein intake

¹ This research was supported in part by the College of Agricultural and Life Sciences and the Graduate School, University of Wisconsin.

Manuscript received 28 March 1983.

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