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Coffee Consumption During Pregnancy: Subsequent Behavioral Abnormalities of the Offspring

Daniel S. Groisser, Pedro Rosso and Myron Winick

Department of Pediatrics and Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, N. Y. 10032

Offspring of rats fed coffee during pregnancy had reduced body, liver, and brain weight at birth. By 30 days postnatally these animals had recovered in size but exhibited increased locomotion, decreased grooming time, and decreased time spent with a novel object. Offspring of dams fed decaffeinated coffee demonstrated reduced liver weight at birth and similar behavioral characteristics at 30 days of age.

KEY WORDS: • caffeine • pregnancy • fetal abnormalities • behavior

Manuscript received 2 November 1981.




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Copyright © 1982 by American Society for Nutrition