QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Morita, A. Articles by Nakano, K. Search for Related Content PubMed PubMed Citation Articles by Morita, A. Articles by Nakano, K.

Effect of Chronic Immobilization Stress on Tissue Distribution of Vitamin A in Rats Fed a Diet with Adequate Vitamin A

Department of Nutritional Regulation, The Research Institute for Biochemical Regulation, Nagoya University, Chikusa, Nagoya 464, Japan

The effect of consecutive daily immobilization stress on the metabolism of vitamin A was studied in rats by following changes in tissue distribution of the vitamin for 14 days. Male rats, fed a diet with adequate vitamin A, were subjected to 4 hours of daily immobilization for 1, 3, 7, 10 or 14 days. Ponderal growth was completely abolished, and serum vitamin A fell markedly. The amount of vitamin A in liver, testes and kidney decreased after the first period of restraint. On the other hand, the amount of vitamin A in adrenal glands increased gradually and reached a maximum (+62.3%) on the 7th day. In conclusion, this experiment showed that daily intermittent immobilization provoked a marked change in distribution of vitamin A in tissues.

KEY WORDS: • immobilization stress • vitamin A distribution

Manuscript received 7 October 1981.