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Journal of Nutrition Vol. 111 No. 8 August 1981, pp. 1494-1496
Copyright © 1981 by American Society for Nutrition
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Achieving and Maintaining Moderate Iron Deficiency in Rats1

Joan Martin, Robert Labbe, Donald Martin and Patti Shores

Departments of Psychiatry and Behavioral Sciences, Laboratory Medicine and Biostatistics, University of Washington, Seattle, WA 98195

A method for achieving and maintaining moderate levels of nutritional iron deficiency in the male albino rat is described. Hemoglobin concentrations and protoporphyrin/heme ratios were the parameters used to assess iron status. The method was based upon the age of the animals when iron-deficient conditions were introduced.

KEY WORDS: • protoporphyrin/heme ratio • hemoglobin index • nutritional iron deficiency

1 Partially supported by NIH grant HD-11680.

Manuscript received 4 March 1981.




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