QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) A correction has been published Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Forsum, E. Articles by Nesheim, M. C. Search for Related Content PubMed PubMed Citation Articles by Forsum, E. Articles by Nesheim, M. C.

Effect of Energy Restriction on Total Heat Production, Basal Metabolic Rate, and Specific Dynamic Action of Food in Rats¹

Cornell University, Division of Nutritional Sciences and Department of Agricultural Engineering, Ithaca, NY 14853 and Department of Animal Husbandry, Swedish University of Agricultural Sciences, S-750 07 Uppsala 7, Sweden

Man and experimental animals are able to adapt to restricted levels of energy intake mainly by a reduction in basal metabolic rate (BMR) while the effects of energy restriction on the specific dynamic action (SDA) of food and the spontaneous activity are less well established. In this study, growing rats were fed ad libitum or restricted amounts of diet during 28–31 days. Then total heat production (THP) and BMR during 22 hours, as well as SDA of a test meal, were measured on individual rats by indirect calorimetry. After the calorimeter study rats were kept in metabolic cages for 6 days after which they were killed and analyzed for total body composition. The energy balance of the rats over the last 7 days of the study was calculated from changes in body composition and measurements of food intake during this period. During the calorimeter experiment an indirect estimation of the spontaneous activity of the rat was made. Results showed that THP, BMR and SDA of restricted rats were significantly lower than for ad libitum-fed rats. From body composition measurements, rats restricted in food intake before the calorimetry study were found to mobilize more protein and less fat compared to rats fed ad libitum until the calorimetry and body composition studies were carried out. No difference in spontaneous activity was observed between the two dietary treatments.

KEY WORDS: • energy intake • specific dynamic action • basal metabolic rate • body composition • heat production

¹ This study was made possible by a scholarship to E. Forsum from the Henning-Throne Holst Foundation, Marabou, Sundbyberg, Sweden. It was also supported by the Swedish Board for Technical Development, STU, and the Agricultural Experiment Station at Cornell University.

Manuscript received 3 March 1981.

This article has been cited by other articles:

				J. L. Trevaskis, T. Coffey, R. Cole, C. Lei, C. Wittmer, B. Walsh, C. Weyer, J. Koda, A. D. Baron, D. G. Parkes, et al. Amylin-Mediated Restoration of Leptin Responsiveness in Diet-Induced Obesity: Magnitude and Mechanisms Endocrinology, November 1, 2008; 149(11): 5679 - 5687. [Abstract] [Full Text] [PDF]

				C. Gelegen, D. A. Collier, I. C. Campbell, H. Oppelaar, and M. J. H. Kas Behavioral, physiological, and molecular differences in response to dietary restriction in three inbred mouse strains Am J Physiol Endocrinol Metab, September 1, 2006; 291(3): E574 - E581. [Abstract] [Full Text] [PDF]

				A. Valle, A. Catala-Niell, B. Colom, F. J. Garcia-Palmer, J. Oliver, and P. Roca Sex-related differences in energy balance in response to caloric restriction Am J Physiol Endocrinol Metab, July 1, 2005; 289(1): E15 - E22. [Abstract] [Full Text] [PDF]